Ting Lei
Sichuan University
22 Papers
Ting Lei is an academic researcher from Sichuan University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 6, co-authored 9 publications.
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Papers
Phagocyte-membrane-coated and laser-responsive nanoparticles control primary and metastatic cancer by inducing anti-tumor immunity.
Chuan Hu,Ting Lei,Yazhen Wang,Jun Cao,Xiaotong Yang,Lin Qin,Rui Liu,Yang Zhou,Fan Tong,Channakeshava Sokke Umeshappa,Huile Gao +10 more
TL;DR: This study provides a promising combinatorial strategy to trigger antitumor immunity in malignancies using M1-macrophage-membrane-coated nanoparticles having laser-responsive, size-changeable, on-demand drug release and prolonged circulation retention properties.
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A tumor-to-lymph procedure navigated versatile gel system for combinatorial therapy against tumor recurrence and metastasis.
Lin Qin,Jun Cao,Jun Cao,Kun Shao,Fan Tong,Zhihang Yang,Ting Lei,Yazhen Wang,Chuan Hu,Channakeshava Sokke Umeshappa,Huile Gao,Nicholas A. Peppas +11 more
TL;DR: In this article, a combinatorial therapy based on a α-cyclodextrin (CD)-based gel system, DOX/ICG/CpG-P-ss-M/CD, fabricated by encapsulating doxorubicin (DOX) and the photothermal agent indocyanine green (ICG), exhibited heat-responsive release of DOX and vaccine-like nanoparticles, along with chemotherapy-and phototherapy-generated abundant tumor-specific antigen storage in situ.
126
Metformin Mediated PD-L1 Downregulation in Combination with Photodynamic-Immunotherapy for Treatment of Breast Cancer
Chuan Hu,Xueqin He,Yuxiu Chen,Xiaotong Yang,Lin Qin,Ting Lei,Yang Zhou,Tao Gong,Yuan Huang,Huile Gao +9 more
TL;DR: This study offers a potential appealing paradigm of synergistic PDT‐triggered immunotherapy by revealing MET‐mediated PD‐L1 downregulation to achieve tumor eradication.
119
Endo/Lysosome-Escapable Delivery Depot for Improving BBB Transcytosis and Neuron Targeted Therapy of Alzheimer's Disease
Lulu Cai,Chuanyao Yang,Chuanyao Yang,Wenfeng Jia,Yuwei Liu,Rou Xie,Ting Lei,Zhihang Yang,Xueqin He,Rongsheng Tong,Huile Gao,Huile Gao +11 more
TL;DR: Overall, this system programmatically targets BBB and neurons, thus, significantly enhances the intracephalic drug accumulation and AD treatment efficacy.
97
Self-Delivered Supramolecular Nanomedicine with Transformable Shape for Ferrocene-Amplified Photodynamic Therapy of Breast Cancer and Bone Metastases
Yi Qin,Fan Tong,Wei Zhang,Yang Zhou,Siqin He,Rou Xie,Ting Lei,Yushan Wang,Shaojun Peng,Zhaofeng Li,Julian Leong,Huile Gao,Ligong Lu +12 more
TL;DR: In vitro and in vivo evaluations verify that through the positive feedback loop, Ce6‐CD/Fc‐pep‐PEG can induce a potent antitumor immune response and achieve ROS‐potentiated elimination of primary tumor and bone metastasis.
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