Ting Fan
Xi'an Jiaotong University
12 Papers
27 Citations
Ting Fan is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Tumor necrosis factor alpha & Chelerythrine. The author has an hindex of 11, co-authored 12 publications.
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Papers
The anti-inflammatory effects of sanguinarine and its modulation of inflammatory mediators from peritoneal macrophages.
TL;DR: The results demonstrated that sanguinarine inhibited the activation of mitogen-activated protein kinase (MAPK), which altered inflammatory mediator synthesis and release in vitro and in vivo and provided clarification of the molecular mechanisms underlying the anti-inflammatory activity of sanguinine.
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Protective effect of tetrahydrocoptisine against ethanol-induced gastric ulcer in mice.
TL;DR: The results suggest that the gastroprotective activity of THC is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression.
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Isofraxidin exhibited anti-inflammatory effects in vivo and inhibited TNF-α production in LPS-induced mouse peritoneal macrophages in vitro via the MAPK pathway.
TL;DR: The data suggest that IF possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
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Isofraxidin protects mice from LPS challenge by inhibiting pro-inflammatory cytokines and alleviating histopathological changes.
TL;DR: Evaluating how IF regulates the production of inflammatory cytokines in vivo by intraperitoneal injection of IF shows that pretreatment with IF increases the survival rate following LPS stimulation in mice, suggesting that IF may have a therapeutic effect against LPS-induced inflammatory disease.
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Anti-inflammatory effect of tetrahydrocoptisine from Corydalis impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide-stimulated peritoneal macrophages through inhibiting NF-κB activation and MAPK pathway.
TL;DR: The data suggest that THC is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phosphO-p38MAPK signal pathways.
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