Timothy M. Cunningham

TL;DR: The coordination environment of Cu¬(+) in the human α1-glycine receptor (GlyR) is identified and it is shown that Cu²(+) has one binding site per α1 subunit, and that five Cuµ(+) can be coordinated per GlyR, and the coordination site does not include several residues of the agonist/antagonist binding site that were previously suggested to have roles in Cu´(+) coordination by functional measurements.