Timothy J. Barnes
University of South Australia
52 Papers
542 Citations
Timothy J. Barnes is an academic researcher from University of South Australia. The author has contributed to research in topics: Chemistry & Adsorption. The author has an hindex of 23, co-authored 43 publications.
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Papers
Silica nanoparticle coated liposomes: A new type of hybrid nanocapsule for proteins
TL;DR: A hybrid silica-liposome nanocapsule system containing insulin has been developed and the encapsulation, protection and release properties are evaluated, showing promise as a delivery vehicle for proteins and peptides.
146
Oxidized Mesoporous Silicon Microparticles for Improved Oral Delivery of Poorly Soluble Drugs
TL;DR: The pSi carrier facilitates accelerated immediate release of IMC and enhanced oral delivery performance in comparison with crystalline indomethacin and Indocid i.e. a 4-times reduction on T(max), a 200% increase on C(max) and a significant increase in bioavailability.
137
Surface chemistry of porous silicon and implications for drug encapsulation and delivery applications.
TL;DR: Porous silicon (pSi) has a number of unique properties that appoint it as a potential drug delivery vehicle; high loading capacity, controllable surface chemistry and structure, and controlled release properties, which allows specific drug release behaviors to be engineered to aid in the delivery of previously challenging therapeutics.
106
Polymer and particle adsorption at the PDMS droplet-water interface.
TL;DR: The PDMS droplets under consideration, having inherent colloid stability in the absence of added stabilisers, are an excellent model system for characterising polymer and particle adsorption at the droplet-water interface and display a pH dependency in line with 'DLVO behaviour'.
53
Mechanistic insight into cell growth, internalization, and cytotoxicity of PAMAM dendrimers.
TL;DR: There is a striking transition from cell growth enhancement to a reduction in cell viability at a critical PAMAM dendrimer concentration, that is, approximately 500 nM, which has significant implications in the design of effective drug/gene delivery vehicles based on dendrilers.
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