Timothy Benjamin
National Institutes of Health
21 Papers
265 Citations
Timothy Benjamin is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Polyacrylamide gel electrophoresis & Membrane glycoproteins. The author has an hindex of 10, co-authored 21 publications.
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Papers
Identification of gel-separated tumor marker proteins by mass spectrometry
Ann Charlotte Bergman,Timothy Benjamin,Ayodele Alaiya,Mark Waltham,Kazuyazu Sakaguchi,Bo Franzén,Stig Linder,Tomas Bergman,Gert Auer,Ettore Appella,Peter J. Wirth,Hans Jörnvall +11 more
TL;DR: The protein processing and the difference between protein and mRNA abundancies in tumors of different malignancy and origin suggest that studies at the protein level are important for an understanding of tumor phenotypes.
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•Journal Article
Sequential Analysis of Chemically Induced Hepatoma Development in Rats by Two Dimensional Electrophoresis
TL;DR: Comparisons showed that roughly 4-10% of the polypeptides were undergoing quantitative changes of at least 4-fold during these stages of hepatocarcinogenesis, and alpha-Fetoprotein was not detected in either preneoplastic or neoplastic nodules.
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Micropreparative immobilized pH gradient two‐dimensional electrophoresis in combination with protein microsequencing for the analysis of human liver proteins
TL;DR: It is shown that micropreparative IPG 2‐D PAGE in combination with protein microsequencing provides a convenient one step procedure to rapidly obtain partial amino acid sequence information for nearly 100 individual polypeptides directly from a single 2‐ D PAGE gel with numerous applications to a wide variety of biological model systems.
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Enzymic N-acetylation of 2,4-toluenediamine by liver cytosols from various species.
Thirayudh Glinsukon,Timothy Benjamin,Preston H. Grantham,Elizabeth K. Weisburger,Peter P. Roller +4 more
TL;DR: In hamsters and rabbits the highest N-acetyltransferase activity was present in the liver cytosol, followed by kidney intestinal mucosa and lung cytosols, and there was a slight difference in the levels of N- acetyltransferases in males and females.
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