Timothy A. Bertram
Tengion
55 Papers
232 Citations
Timothy A. Bertram is an academic researcher from Tengion. The author has contributed to research in topics: Regenerative medicine & Regeneration (biology). The author has an hindex of 14, co-authored 48 publications.
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Papers
Tubular cell-enriched subpopulation of primary renal cells improves survival and augments kidney function in rodent model of chronic kidney disease
Rusty Kelley,Eric S. Werdin,Andrew T. Bruce,Sumana Choudhury,Shay M. Wallace,Roger M. Ilagan,Bryan R. Cox,Patricia Tatsumi-Ficht,Elias A. Rivera,Thomas Spencer,H. Scott Rapoport,Belinda J. Wagner,Kelly I. Guthrie,Manuel J. Jayo,Timothy A. Bertram,Sharon C. Presnell +15 more
TL;DR: The effect of kidney cells, delivered orthotopically by intraparenchymal injection to rodents 4-7 wk after CKD was established by two-step 5/6 renal mass reduction (NX), on the regeneration of kidney function and architecture as assessed by physiological, tissue, and molecular markers is evaluated.
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Patent
Scaffolds for organ reconstruction and augmentation
Timothy A. Bertram,Andrew T. Bruce,Deepak Jain,Manuel J. Jayo,John W. Ludlow,Darell W. McCoy,Richard G. Payne,Namrata Sangha +7 more
- 12 Feb 2007
TL;DR: In this paper, synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation, or replacement of organs or tissue structures in a patient in need of such treatment.
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Hurdles in tissue engineering/regenerative medicine product commercialization: a pilot survey of governmental funding agencies and the financial industry.
TL;DR: It is indicated that under the current financial environment, many regenerative medical companies must consider codevelopment or even M&A as nondilutive means of raising capital.
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Isolation, characterization, and expansion methods for defined primary renal cell populations from rodent, canine, and human normal and diseased kidneys.
Sharon C. Presnell,Andrew T. Bruce,Shay M. Wallace,Sumana Choudhury,Christopher W. Genheimer,Bryan R. Cox,Kelly I. Guthrie,Eric S. Werdin,Patricia Tatsumi-Ficht,Roger M. Ilagan,Russell W. Kelley,Elias A. Rivera,John W. Ludlow,Belinda J. Wagner,Manuel J. Jayo,Timothy A. Bertram +15 more
TL;DR: Methods that yield distinct subpopulations of primary kidney cells that are compatible with process development and scale-up are developed, suggesting that autologous sourcing of cells that contribute to in situ kidney regeneration after injury is feasible, even with biopsies from patients with advanced CKD.
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Patent
Cell scaffold constructs
John W. Ludlow,Manuel J. Jayo,Joydeep Basu,Timothy A. Bertram,Christopher W. Genheimer,Kelly I. Guthrie,Roger M. Ilagan,Deepak Jain,Oluwatoyin A. Knight,Richard G. Payne,Sarah F. Quinlan,H. Scott Rapoport,Namrata Sangha +12 more
- 04 Nov 2009
TL;DR: In this article, the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
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