Timo Eninger
German Center for Neurodegenerative Diseases
4 Papers
26 Citations
Timo Eninger is an academic researcher from German Center for Neurodegenerative Diseases. The author has contributed to research in topics: Genetically modified mouse & Synucleinopathies. The author has an hindex of 1, co-authored 3 publications. Previous affiliations of Timo Eninger include University of Tübingen.
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Papers
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases.
Mehtap Bacioglu,Luis F. Maia,Oliver Preische,Juliane Schelle,Juliane Schelle,Anja Apel,Stephan A. Kaeser,Manuel Schweighauser,Manuel Schweighauser,Timo Eninger,Timo Eninger,Marius Lambert,Marius Lambert,Andrea Pilotto,Andrea Pilotto,Derya R. Shimshek,Ulf Neumann,Philipp J. Kahle,Philipp J. Kahle,Matthias Staufenbiel,Matthias Staufenbiel,Manuela Neumann,Walter Maetzler,Walter Maetzler,Jens Kuhle,Mathias Jucker,Mathias Jucker +26 more
TL;DR: It is suggested that CSF and particularly blood NfL can serve as a reliable and easily accessible biomarker to monitor disease progression and treatment response in mouse models and potentially in human proteopathic neurodegenerative diseases.
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LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
Marc Emmenegger,Elena De Cecco,Marian Hruska-Plochan,Timo Eninger,Timo Eninger,Matthias Schneider,Melanie Barth,Melanie Barth,Elena Tantardini,Pierre De Rossi,Mehtap Bacioglu,Mehtap Bacioglu,Rebekah G. Langston,Alice Kaganovich,Nora Bengoa-Vergniory,Andrés González-Guerra,Merve Avar,Daniel Heinzer,Regina Reimann,Lisa M. Häsler,Lisa M. Häsler,Therese W. Herling,Naunehal S. Matharu,Natalie Landeck,Kelvin C. Luk,Ronald Melki,Philipp J. Kahle,Philipp J. Kahle,Simone Hornemann,Tuomas P. J. Knowles,Mark R. Cookson,Magdalini Polymenidou,Mathias Jucker,Mathias Jucker,Adriano Aguzzi +34 more
TL;DR: In this article, the expression pattern of LAG3 in human and mouse brains was analyzed, and it was shown that LAG-3 interacts with α-synuclein fibrils, but the specificity of this interaction appears limited.
Signatures of glial activity can be detected in the CSF proteome
Timo Eninger,Stephan A. Müller,Mehtap Bacioglu,Manuel Schweighauser,Marius Lambert,Luis F. Maia,Jonas J. Neher,Sarah M Hornfeck,Ulrike Obermüller,Gernot Kleinberger,Christian Haass,Philipp J. Kahle,Matthias Staufenbiel,Lingyan Ping,Duc M. Duong,Allan I. Levey,Nicholas T. Seyfried,Stefan F. Lichtenthaler,Mathias Jucker,Stephan A. Kaeser +19 more
TL;DR: Proteome analysis in cerebrospinal fluid of mouse models of AD and PD pathology allowed us to identify a panel of glial CSF proteins that largely match the transcriptomic changes, supporting their relevance as biomarker candidates to stage glial activation in patients with neurodegenerative diseases.
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LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
Marc Emmenegger,Elena De Cecco,Marian Hruska-Plochan,Timo Eninger,Timo Eninger,Matthias Schneider,Melanie Barth,Melanie Barth,Elena Tantardini,Pierre De Rossi,Mehtap Bacioglu,Mehtap Bacioglu,Rebekah G. Langston,Alice Kaganovich,Nora Bengoa-Vergniory,Andrés González-Guerra,Merve Avar,Daniel Heinzer,Regina Reimann,Lisa M. Häsler,Lisa M. Häsler,Therese W. Herling,Naunehal S. Matharu,Natalie Landeck,Kelvin C. Luk,Ronald Melki,Philipp J. Kahle,Philipp J. Kahle,Simone Hornemann,Tuomas P. J. Knowles,Mark R. Cookson,Magdalini Polymenidou,Mathias Jucker,Mathias Jucker,Adriano Aguzzi +34 more
TL;DR: In this article, the expression pattern of LAG3 in human and mouse brains was analyzed, and it was found that LAG-3 interacts with α-synuclein fibrils, but the specificity of this interaction appears limited.