Tim Connallon
Monash University, Clayton campus
78 Papers
277 Citations
Tim Connallon is an academic researcher from Monash University, Clayton campus. The author has contributed to research in topics: Population & Biology. The author has an hindex of 25, co-authored 60 publications. Previous affiliations of Tim Connallon include Monash University & Cornell University.
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Papers
The faster-X effect: integrating theory and data
Richard P. Meisel,Tim Connallon +1 more
TL;DR: It is indicated that the faster-X effect is pervasive across a taxonomically diverse array of evolutionary lineages and could be informative of the dominance or recessivity of beneficial mutations and the nature of genetic variation acted upon by natural selection.
279
Balancing selection in species with separate sexes: insights from fisher's geometric model
Tim Connallon,Andrew G. Clark +1 more
TL;DR: It is shown that balancing selection is common under biologically plausible conditions and that sex differences in selection or sex-by-genotype effects of mutations can each increase opportunities for balancing selection.
Horizontal gene transfer potentiates adaptation by reducing selective constraints on the spread of genetic variation
TL;DR: It is shown that HGT can help antibiotic resistance genes establish at a low frequency in a population, even in the absence of the antibiotic, and increases the rate of adaptation, with most horizontally transferred genetic variants establishing at aLow frequency in the population.
99
Coadaptation of mitochondrial and nuclear genes, and the cost of mother’s curse
TL;DR: A population genetic analysis of mito-nuclear coadaptation to resolve mother's curse effects shows that the magnitude of the ‘male mitochondrial load’—the negative impact of mitochondrial substitutions on male fitness components—may be large, even when genetic variation for compensatory evolution is abundant.
Association between Sex-Biased Gene Expression and Mutations with Sex-Specific Phenotypic Consequences in Drosophila
Tim Connallon,Andrew G. Clark +1 more
TL;DR: It is found that mutations in female-biased genes are (on average) more deleterious to females than to males and that mutations that have been mapped to the Drosophila melanogaster genome tend to be more deleTERious to males than to females.