Tianyou Wang
Boston Children's Hospital
8 Papers
18 Citations
Tianyou Wang is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Biology & Mesenchymal stem cell. The author has an hindex of 4, co-authored 4 publications.
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Papers
Human umbilical cord mesenchymal stem cells alleviate interstitial fibrosis and cardiac dysfunction in a dilated cardiomyopathy rat model by inhibiting TNF‑α and TGF‑β1/ERK1/2 signaling pathways
Changyi Zhang,Guichi Zhou,Yezeng Chen,Sizheng Liu,Fen Chen,Lichun Xie,Wei Wang,Yonggang Zhang,Tianyou Wang,Xiulan Lai,Lian Ma +10 more
TL;DR: It is suggested that HuMSC injections attenuated myocardial fibrosis and dysfunction in a rat model of DCM, likely by inhibiting TNF-α and the TGF-β1/ERK1/2 fibrosis pathways.
Single-Cell Transcriptome Integration Analysis Reveals the Correlation Between Mesenchymal Stromal Cells and Fibroblasts
Chuiqin Fan,Maochuan Liao,Lichun Xie,Liangping Huang,Siyu Lv,S Cai,Xing Su,Yu Wang,Hongwu Wang,Manna Wang,Yulin Liu,Yu Wang,Hui-yu Guo,Hanhua Yang,Yufeng Liu,Tianyou Wang,Lian Ma +16 more
TL;DR: It is demonstrated that the MSCs and fibroblasts represented highly heterogeneous populations with distinct cell subsets, which could be identified based on the differentially enriched gene sets and regulons that specify proliferating, differentiating, metabolic, and/or immunomodulatory functions.
Downregulation of TrkA protein expression by miRNA‑92a promotes the proliferation and migration of human neuroblastoma cells.
TL;DR: In this article, the authors investigated the regulation of TrkA protein by micro (mi)RNA-92a and its effect on the proliferation and migration of human neuroblastoma cells.
A correlation analysis of miRNA‑34a and its predicted target genes in leukemia.
TL;DR: The expression of miR‑34a negatively correlates with the expression of CDK4 and MYB in pediatric patients with acute leukemia, and may represent a novel therapeutic target for acute leukemia.
Proteomic and phosphorylated proteomic landscape of injured lung in juvenile septic rats with therapeutic application of umbilical cord mesenchymal stem cells
Hongwu Wang,Junli Luo,Aijia Li,Xing Su,Chuiqin Fang,Lichun Xie,Yi Wu,Feiqiu Wen,Yufeng Liu,Tianyou Wang,Yong Zhong,Lian Ma +11 more
TL;DR: Results from proteomics and phosphorylated proteomics showed that tight junction pathway was closely related to immune inflammatory reaction, and EGFR interacted most, which may be the key differential phosphorylation protein.