Thomas K. Andreassen
Aarhus University
5 Papers
123 Citations
Thomas K. Andreassen is an academic researcher from Aarhus University. The author has contributed to research in topics: Receptor & Hormone. The author has an hindex of 4, co-authored 4 publications.
Chat about Author
Papers
Role of endocytosis in cellular uptake of sex steroids.
Annette Hammes,Thomas K. Andreassen,Robert Spoelgen,Jens Raila,Norbert Hubner,Herbert Schulz,Jochen Metzger,Florian J. Schweigert,Peter B. Luppa,Andreas Nykjaer,Thomas E. Willnow +10 more
TL;DR: It is demonstrated that megalin, an endocytic receptor in reproductive tissues, acts as a pathway for cellular uptake of biologically active androgens and estrogens bound to sex hormone binding globulin.
428
Essential Role of the Apolipoprotein E Receptor-2 in Sperm Development
Olav M. Andersen,Ching-Hei Yeung,Henrik Vorum,Maren Wellner,Thomas K. Andreassen,Bettina Erdmann,Eva-Christina Mueller,Joachim Herz,Albrecht Otto,Trevor G. Cooper,Thomas E. Willnow +10 more
TL;DR: It is demonstrated that apoER2 is highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation.
108
Cellular uptake of lipoproteins and persistent organic compounds--an update and new data.
TL;DR: It is concluded that DDT travels in the blood stream and can cross cell membranes while being transported as a DDT-lipoprotein complex, and the lipoproteins do not need receptors toCross cell membranes since passive diffusion constitutes a major passageway.
20
Rabbit Development as a Model for Single Cell Comparative Genomics
Mai-Linh N Ton,Daniel Keitley,Bart Theeuwes,Carolina Guibentif,Jonas Ahnfelt-Rønne,Thomas K. Andreassen,Fernando J Calero-Nieto,Ivan Imaz-Rosshandler,Blanca Pijuan-Sala,Jennifer Nichols,lia Benito-Gutiérrez,John C. Marioni,Berthold Göttgens +12 more
TL;DR: This study constructed a morphological and molecular atlas of rabbit development, which like the human embryo, develops as a flat-bilaminar disc, and compares the transcriptional landscape of rabbit and mouse at the scale of the entire organism, revealing that extra-embryonic tissues, as well as gut and PGC cell types, are highly divergent between species.
Hyporesponsiveness to glucocorticoids in mice genetically deficient for the corticosteroid binding globulin.
Helle Heibroch Petersen,Thomas K. Andreassen,Tilman Breiderhoff,Jan Hinrich Bräsen,Herbert Schulz,Volkmar Gross,Hermann Josef Gröne,Anders Nykjaer,Thomas E. Willnow +8 more
TL;DR: An active role for CBG in bioavailability, local delivery, and/or cellular signal transduction of glucocorticoids that extends beyond a function as a mere cargo transporter is suggested.