Thomas J. Matula
University of Washington
150 Papers
971 Citations
Thomas J. Matula is an academic researcher from University of Washington. The author has contributed to research in topics: Sonoluminescence & Microbubbles. The author has an hindex of 32, co-authored 147 publications. Previous affiliations of Thomas J. Matula include Université libre de Bruxelles & Johns Hopkins University Applied Physics Laboratory.
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Papers
Blood vessel deformations on microsecond time scales by ultrasonic cavitation.
TL;DR: Observations of transient interactions among ultrasound, microbubbles, and microvessels provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.
Vascular effects induced by combined 1-MHz ultrasound and microbubble contrast agent treatments in vivo.
Joo Ha Hwang,Andrew A. Brayman,Michael A. Reidy,Thomas J. Matula,Michael B. Kimmey,Lawrence A. Crum +5 more
TL;DR: Five specific hypotheses were tested in an in vivo rabbit auricular blood vessel model that acoustic cavitation nucleated by microbubble contrast agent can damage the endothelia of veins at relatively low spatial-peak temporal-average intensities and ultrasound/contrast agent-induced endothelial damage can be inherently thrombogenic, or can aid sclerotherapeuticThrombogenesis through the application of otherwise subtherapeutic doses of thromBogenic drugs.
234
Inertial cavitation dose and hemolysis produced in vitro with or without Optison.
TL;DR: Within series, hemolysis was significantly correlated with ICD; across series, the correlation was significant at p < 0.001.
202
The pulse length-dependence of inertial cavitation dose and hemolysis.
TL;DR: Gas-based ultrasound (US) contrast agents increase erythrocyte sonolysis, presumably via enhancing inertial cavitation (IC) activity, and the amount of IC activity and hemolysis generated by exposure to 1.15 MHz US were examined.
151
Estimating the shell parameters of SonoVue® microbubbles using light scattering
TL;DR: The results suggest that light scattering, used in conjunction with one of several popular bubble dynamics models, is effective at characterizing microbubble response and evaluating shell parameters.