Thomas J. Goodwin
25 Papers
385 Citations
Thomas J. Goodwin is an academic researcher. The author has contributed to research in topics: Cell culture & Biology. The author has an hindex of 16, co-authored 24 publications.
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Papers
Three-dimensional co-culture models to study prostate cancer growth, progression, and metastasis to bone.
Ruoxiang Wang,Jianchun Xu,Lisa Juliette,Agapito Castilleja,John E. Love,Shian Ying Sung,Haiyen E. Zhau,Thomas J. Goodwin,Leland W.K. Chung +8 more
TL;DR: It is suggested that cancer-stromal interaction can best be investigated by three-dimensional (3D) co-culture models with the results validated by clinical specimens, and showed that 3D culture promoted bone formation in vitro.
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Changes in gravity inhibit lymphocyte locomotion through type I collagen
Neal R. Pellis,Thomas J. Goodwin,Diana Risin,Bradley W. McIntyre,Roland P. Pizzini,David Cooper,Tacey L. Baker,Glenn F. Spaulding +7 more
TL;DR: In vitro investigations suggest that microgravity induces non-stress-related changes in cell function that may be critical to immunity, as well as characterize potential causes of microgravity-induced immunosuppression.
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Establishment of a three-dimensional human prostate organoid coculture under microgravity-simulated conditions: evaluation of androgen-induced growth and PSA expression.
TL;DR: The microgravity-simulated three-dimensional prostate epithelial cell culture with prostate fibroblasts can be further explored as an ideal in vitro model for the study of normal and neoplastic prostate development.
84
Patent
Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof
David A. Wolf,Thomas J. Goodwin +1 more
- 28 Feb 2001
TL;DR: In this article, the authors present a system for growing two or three dimensional mammalian cells within a culture medium facilitated by an electromagnetic field, and preferably a time varying electromagnetic field. And they further provide methods to promote neural tissue regeneration by means of culturing the neural cells in the claimed system.
Three-dimensional culture of bovine chondrocytes in rotating-wall vessels.
Tacey L. Baker,Thomas J. Goodwin +1 more
TL;DR: The Rotating-Wall Vessel was used to culture chondrocytes for 36 d to observe the influence of low-shear and quiescent culture conditions allowing three-dimensional freedom on growth, differentiation, and extracellular matrix formation, indicating that the unique conditions provided by the RWV afford access to cellular processes that signify the initiation of differentiation as well as production of normal matrix material.
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