Aspects of the invention relate to compositions comprising one or more live bacterial strains for topical administration to the skin, wherein the one or more live bacterial strains are Propionibacterium acnes ( P . acnes ) bacterial strains, and methods for use.

Methods and compositions for changing the composition of the skin microbiome using complex mixtures of bacterial strains

A method and system for the treatment of honey bees ( Apis mellifera ), bats, and butterflies protects them from various life threatening conditions, including Colony Collapse Disorder, white nose syndrome, etc and in particular, provides honey bees, bats and butterflies with the ability to assimilate and degrade neonicotinoids

Method and System for Protecting Honey Bees, Bats and Butterflies From Neonicotinoid Pesticides

A method and system for addressing the avoidance of migraines, cluster headaches and dizziness by adjusting an individual's microbiome, and in particular, to the provision of beneficial oral and gut microbes at particular times to enhance a person's oral health, including through the use of oral strips that adhere to surfaces in the oral cavity.

Method and system for preventing migraine headaches, cluster headaches and dizziness

Disclosed are synthetic bacteria having de novo metabolic pathways for biosynthesis of select compounds. Further disclosed are methods of use to prevent and treat skin disorders and diseases.

Synthetic bacteria and methods of use

The invention is directed to recombinant probiotic bacteria, especially for use in the treatment of an inflammatory skin dysfunction, as well as a method for treating an inflammatory skin dysfunction.

Recombinant probiotic bacteria

Microbes can be genetically modified to express biomolecules that are beneficial to mammals and/or to reduce, or eliminate, expression of harmful virulence factors. The growth and viability of such genetically modified microbes can optionally be controlled by inducible promoters that regulate the expression of proteins that are essential to their growth and survival. Compositions comprising such genetically modified microbes as well as methods of making and using the same are disclosed herein.

Genetically modified bacteria and methods for genetic modification of bacteria

Skin probiotic formulation

Genetically modified bacteria, compositions and methods of making and using

To provide pharmaceutical compositions for a field of dermatology and for topical dermatological purposes, the pharmaceutical compositions containing genetically modified bacteria.SOLUTION: This invention relates to pharmaceutical compositions prepared for administration to mammal, wherein: the compositions comprise a genetically modified Propionibacterium acnes strain (P. acnes strain) that contains a control factor operatably connected to a nucleic acid encoding a mammalian growth factor or a mammalian cytokine; the strain expresses the mammalian growth factor or the mammalian cytokine; the P. acnes strain a CRISPR array; and the control factor and the nucleic acid are integrated into a genome of the P. acnes strain.SELECTED DRAWING: None

Composition containing genetically modified propionibacterium acnes, and genetically modified bacteria of propionibacterium acnes strain

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Genetically modified bacteria and methods for genetic modification of bacteria

Skin probiotic formulation

Genetically modified bacteria, compositions and methods of making and using

Composition containing genetically modified propionibacterium acnes, and genetically modified bacteria of propionibacterium acnes strain