Thomas Helbing
University of Freiburg
37 Papers
66 Citations
Thomas Helbing is an academic researcher from University of Freiburg. The author has contributed to research in topics: Medicine & Endothelial stem cell. The author has an hindex of 20, co-authored 36 publications. Previous affiliations of Thomas Helbing include University of Oldenburg.
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Papers
Microparticles: major transport vehicles for distinct microRNAs in circulation
Philipp Diehl,Philipp Diehl,Alba Fricke,Laura Sander,Johannes Stamm,Nicole Bassler,Nay Chi Htun,Nay Chi Htun,Mark Ziemann,Thomas Helbing,Assam El-Osta,Assam El-Osta,Jeremy B. M. Jowett,Jeremy B. M. Jowett,Karlheinz Peter,Karlheinz Peter +15 more
TL;DR: Findings describe an interesting mechanism for transferring gene-regulatory function from MP-releasing cells to target cells via MP circulating in blood, which represents transport vehicles for large numbers of specific miRNAs, which have been associated with cardiovascular diseases.
496
BMPER Is an Endothelial Cell Regulator and Controls Bone Morphogenetic Protein-4–Dependent Angiogenesis
Jennifer Heinke,Leonie Wehofsits,Qian Zhou,Christoph Zoeller,Kim Miriam Baar,Thomas Helbing,Anna M. Laib,Hellmut G. Augustin,Christoph Bode,W. Cam Patterson,Martin Moser +10 more
TL;DR: BMPER is a dose-dependent endothelial cell activator that plays a unique and pivotal role in fine-tuning BMP activity in angiogenesis.
155
Complex Plaques in the Proximal Descending Aorta An Underestimated Embolic Source of Stroke
Andreas Harloff,Jan C. Simon,Stefanie M. Brendecke,Dawit Assefa,Thomas Helbing,Alex Frydrychowicz,Johannes Weber,Manfred Olschewski,Christoph Strecker,Jürgen Hennig,Cornelius Weiller,Michael Markl +11 more
TL;DR: In this paper, the authors investigated the incidence of retrograde flow from complex plaques (4mm-thick, ulcerated, or superimposed thrombi) of the descending aorta and its potential role in embolic stroke.
148
MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy
Franziska Pankratz,Catherine Hohnloser,Xavier Bemtgen,Caterina Jaenich,Sheena Kreuzaler,Imo E. Hoefer,Gerard Pasterkamp,Justin Mastroianni,Robert Zeiser,Christian Smolka,Laura A Schneider,Julien Martin,Maike Juschkat,Thomas Helbing,Martin Moser,Christoph Bode,Sebastian Grundmann +16 more
TL;DR: The findings of miR-100 as a potential protective anti-athero-miR suggest that the therapeutic replacement of this microRNA could be a potential strategy for the treatment of chronic inflammatory diseases, such as atherosclerosis, in the future.
112
Increased levels of circulating microparticles in patients with severe aortic valve stenosis.
Philipp Diehl,Ferenc Nagy,Verena Sossong,Thomas Helbing,Friedhelm Beyersdorf,Manfred Olschewski,Christoph Bode,Martin Moser +7 more
TL;DR: It is shown that AVS is accompanied by increased levels of microparticles and that shear stress can induce the formation ofmicroparticles.
98