Thomas G. Hampton
Beth Israel Deaconess Medical Center
41 Papers
268 Citations
Thomas G. Hampton is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Gait (human) & Medicine. The author has an hindex of 21, co-authored 41 publications.
Chat about Author
Papers
PR39, a peptide regulator of angiogenesis
Jian Li,Mark J. Post,Ruediger Volk,Youhe Gao,M Li,Caroline Metais,Koichiro Sato,Jo C. Tsai,William C. Aird,Robert D. Rosenberg,Thomas G. Hampton,Frank W. Sellke,Peter Carmeliet,Michael Simons +13 more
TL;DR: It is shown that a macrophage-derived peptide, PR39, inhibited the ubiquitin–proteasome-dependent degradation of hypoxia-inducible factor-1α protein, resulting in accelerated formation of vascular structures in vitro and increased myocardial vasculature in mice.
445
Gait dynamics in mouse models of Parkinson's disease and Huntington's disease
TL;DR: The distinct characteristics of gait and gait variability in the MPTP model of Parkinson's disease and the 3NP model of Huntington's disease may reflect impairment of specific neural pathways involved.
Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins
Yun Bian,Maoyun Sun,Marcy Silver,Kalon K.L. Ho,Mark A. Marchionni,Anthony O. Caggiano,James R. Stone,Ivo Amende,Thomas G. Hampton,James P. Morgan,Xinhua Yan +10 more
TL;DR: NRG1 attenuates Dox-induced decrease in cardiac troponins by increasing transcription and translation and by inhibiting caspase activation and proteasome degradation of troponin proteins, which may lessen Dox -induced cardiac dysfunction.
88
Electrocardiographic findings in mdx mice: A cardiac phenotype of Duchenne muscular dystrophy
Victor Chu,Jose M. Otero,Orlando Lopez,Matthew F. Sullivan,James P. Morgan,Ivo Amende,Thomas G. Hampton +6 more
TL;DR: Baseline ECGs and contrary responses to muscarinic blockade by atropine in mice deficient in neuronal nitric oxide synthase (nNOS) suggest that the autonomic dysfunction in mdx mice may be independent of decreased myocardial nNOS.
76
Cardiovascular Abnormalities in Transgenic Mice With Reduced Brown Fat An Animal Model of Human Obesity
Antonio Cittadini,Christos S. Mantzoros,Thomas G. Hampton,Kerry E. Travers,Sarah E. Katz,James P. Morgan,Jeffrey S. Flier,Pamela S. Douglas +7 more
TL;DR: Transgenic ablation of brown adipose tissue is associated not only with obesity but also with systemic hypertension, left ventricular hypertrophy with eccentric remodeling and fibrosis, and high cardiac output, a unique constellation of findings strikingly similar to that seen in human obesity.
63