Thomas B. Cook
Mercyhurst University
9 Papers
35 Citations
Thomas B. Cook is an academic researcher from Mercyhurst University. The author has contributed to research in topics: Kynurenine & Toxoplasma gondii. The author has an hindex of 7, co-authored 9 publications. Previous affiliations of Thomas B. Cook include Baldwin Wallace University.
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Papers
"Latent" infection with Toxoplasma gondii: association with trait aggression and impulsivity in healthy adults
Thomas B. Cook,Lisa A. Brenner,C. Robert Cloninger,Patricia Langenberg,Ajirioghene Igbide,Ina Giegling,Annette M. Hartmann,Bettina Konte,Marion Friedl,Lena Brundin,Maureen Groer,Adem Can,Dan Rujescu,Teodor T. Postolache +13 more
TL;DR: Aggression and impulsivity, personality traits considered as endophenotypes for SSDV, are associated with latent T. gondii infection in a gender and age-specific manner, and could be further investigated as prognostic and treatment targets in T. Gondii-positive individuals at risk of suicidal self-directed violence.
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Persistence of racial disparities in prescription of first-generation antipsychotics in the USA.
TL;DR: The aim of this study was to estimate the prevalence of first‐generation antipsychotics prescribed for treatment of psychiatric and neurological conditions and use of benztropine to reduce extrapyramidal side effects by patient race/ethnicity in a nationally representative sample of adult outpatient visits.
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Kynurenine and Tryptophan Levels in Patients With Schizophrenia and Elevated Antigliadin Immunoglobulin G Antibodies.
Olaoluwa O. Okusaga,Dietmar Fuchs,Gloria Reeves,Ina Giegling,Annette M. Hartmann,Bettina Konte,Marion Friedl,Maureen Groer,Thomas B. Cook,Kelly A. Stearns-Yoder,Janardan P. Pandey,Deanna L. Kelly,Andrew J. Hoisington,Christopher A. Lowry,William W. Eaton,Lisa A. Brenner,Dan Rujescu,Teodor T. Postolache +17 more
TL;DR: The results connect nonceliac gluten sensitivity with the KYN pathway of TRP metabolism in psychotic illness and hint toward potential individualized treatment targets.
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Moderation of the Relationship between Toxoplasma gondii Seropositivity and Trait Impulsivity in Younger Men by the Phenylalanine-Tyrosine Ratio
Xiaoqing Peng,Lisa A. Brenner,Ashwin Jacob Mathai,Thomas B. Cook,Dietmar Fuchs,Nadine Postolache,Maureen Groer,Janardan P. Pandey,Farooq Mohyuddin,Ina Giegling,Abhishek Wadhawan,Annette M. Hartmann,Bettina Konte,Lena Brundin,Marion Friedl,John W. Stiller,Christopher A. Lowry,Dan Rujescu,Teodor T. Postolache +18 more
TL;DR: Phe:Tyr ratio may play a moderating role in the association between T. gondii seropositivity and impulsivity in younger men, and could potentially lead to individualized approaches to reduce impulsivity, based on combined demographic, biochemical and serological factors.
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Is latent infection with Toxoplasma gondii a risk factor for suicidal behavior
TL;DR: Toxoplasma gondii, with its ability to both evade and manipulate the host immune system and its affinity for privileged sites in the CNS, can potentially operate at multiple pathways to increase risk of suicidal self-directed violence.
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