Thierry Humbert
Centre national de la recherche scientifique
6 Papers
36 Citations
Thierry Humbert is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Pentadecanoic acid & Yield (chemistry). The author has an hindex of 3, co-authored 6 publications.
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Papers
A convenient one-pot synthesis of cyclam-β-cyclodextrins new ligands
TL;DR: In this paper, the one-pot synthesis of polyazamacrocyclic compounds was described, having hydrophobic hosts cavities (β-cyclodextrins) attached to a metal chelating aza-macrocycle by ureido spacer arms.
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Heptakis-6-(5-methylene-ureido-5′-methyl-2,2′-bipyridinyl)-cyclomaltoheptaose as a new fluorescent lanthanide polydentate ligand
TL;DR: In this article, a one-pot synthesis of an heptakis-(bipyridinyl-ureido)-β-cyclodextrin in a high coupling average (82%) by the "phosphinimine" approach was described.
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Synthesis of 3-methyl-15-phenyl-[carboxyl-14C]-pentadecanoic acid
TL;DR: In this article, B-Methyl-15-phenyl-pentadecanoic acid with carbon-14 was obtained with good yield in two steps from Na14CN, starting from 14-methyl 1-methyl tetradecanol methanesulfonate with a specific radioactivity: 108.25 μCi/mg, 1.92 mCi /mmol and in a radiochemical yield of 50% of the theoretical amount.
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Synthesis of 3-methyl-15-(p-iodophenyl)-pentadecanoic acid labelled with carbon-14
TL;DR: Methyl-(p-iodophenyl)-pentadecanoic acid 4 labelled with carbon-14 in the carboxyl group was obtained in 38% radiochemical yield in five steps from Na 14CN at a specific radioactivity of 0.084 mCi/mg.
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Influence of the presence of a methyl group on the myocardial metabolism of 15-(paraiodophenyl)-3 methyl pentadecanoic acid (IMPPA)
Thierry Humbert,Christiane Keriel,Danièle Marti Batlle,Xavier Leverve,Cuong Luu-Duc,Pierre Cuchet,M. Comet +6 more
TL;DR: Comparison of results obtained with IMPPA and MPPA showed that the presence of iodine in the molecule accentuates the inhibition of activation and the retention of myocardial activity is due to intracellular accumulation of free IMPPA following inhibition ofactivation.
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