Therese Eldh
University of Tübingen
11 Papers
Therese Eldh is an academic researcher from University of Tübingen. The author has contributed to research in topics: Lung & Pneumonitis. The author has an hindex of 11, co-authored 11 publications.
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Papers
Formation and maintenance of Alzheimer's disease |[beta]|-amyloid plaques in the absence of microglia
Stefan A. Grathwohl,Roland E. Kälin,Tristan Bolmont,Tristan Bolmont,Stefan Prokop,Georg Winkelmann,Stephan A. Kaeser,Stephan A. Kaeser,Jörg Odenthal,Jörg Odenthal,Rebecca Radde,Rebecca Radde,Therese Eldh,Sam Gandy,Adriano Aguzzi,Matthias Staufenbiel,Paul M. Mathews,Paul M. Mathews,Hartwig Wolburg,Frank L. Heppner,Mathias Jucker,Mathias Jucker +21 more
TL;DR: This work crossed two distinct APP transgenic mouse strains with CD11b-HSVTK mice, in which nearly complete ablation of microglia was achieved for up to 4 weeks after ganciclovir application, suggesting that neither amyloid plaque formation and maintenance nor amyloids-associated neuritic dystrophy depended on the presence ofmicroglia.
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Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway.
Daniel Habermehl,Bernd Kammerer,René Handrick,Therese Eldh,Charlotte Gruber,Nils Cordes,Peter T. Daniel,Ludwig Plasswilm,Michael Bamberg,Claus Belka,Verena Jendrossek +10 more
TL;DR: The potent proapoptotic effects of Ukrain are not due to the suggested "Ukrain-molecule" but to the cytotoxic efficacy of Chelidonium majus L. alkaloid chelidonine and the alkylans thiotepa.
Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury
Janek Henes,Marthe A. Schmit,Marthe A. Schmit,Julio C. Morote-Garcia,Valbona Mirakaj,David Köhler,Louise E. Glover,Therese Eldh,Ulrich Walter,Jörn Karhausen,Sean P. Colgan,Peter Rosenberger +11 more
TL;DR: Tissue‐specific VASP is identified as a central protein in the control of the alveolar‐capillary barrier properties during ALI, andlammation‐associated repression of vasodilator‐stimulated phosphoprotein (VASP) reduces alve SolarCapillary barrier function during acute lung injury.
46
Phosphorylation of Vasodilator-Stimulated Phosphoprotein (VASP) Dampens Hepatic Ischemia-Reperfusion Injury
David Köhler,Philipp Birk,Klemens König,Andreas Straub,Therese Eldh,Julio C. Morote-Garcia,Peter B. Rosenberger +6 more
TL;DR: VASP −/− animals demonstrate reduced hepatic IR injury compared to wildtype (WT) controls and VASP phosphorylation is identified as crucial target for future hepatoprotective strategies.
15
New insights into the molecular pathology of radiation-induced pneumopathy.
Federica Cappuccini,Therese Eldh,Dunja Bruder,Marcus Gereke,Holger Jastrow,Klaus Schulze-Osthoff,Ute Fischer,David Köhler,Martin Stuschke,Verena Jendrossek +9 more
TL;DR: Thorax irradiation triggers a delayed disturbance of tissue integrity and lipid metabolism in the lung, and activated T-lymphocytes infiltrating the lung tissue upon thorax irradation participate in the protection of the lung from radiation-induced fibrosis.