Tetsuo Kida
Kagoshima University
15 Papers
57 Citations
Tetsuo Kida is an academic researcher from Kagoshima University. The author has contributed to research in topics: Difluprednate & Medicine. The author has an hindex of 7, co-authored 12 publications.
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Papers
Bepotastine besilate, a highly selective histamine H1 receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models
Tetsuo Kida,Atsuko Fujii,Osamu Sakai,Masahito Iemura,Ikuyo Atsumi,Tomoyuki Wada,Hideyuki Sakaki +6 more
TL;DR: Bepotastine besilate was more potent than olopatadine, ketotifen, or levocabastine in reducing vascular hyperpermeability in various animal models of allergic conjunctivitis and Mast cell function and eosinophil chemotaxis were inhibited in vitro with bepotastine, suggesting bepotASTine acts as an inhibitor of allergic response through multiple mechanisms.
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Pharmacokinetics and Efficacy of Topically Applied Nonsteroidal Anti-Inflammatory Drugs in Retinochoroidal Tissues in Rabbits
TL;DR: Topical bromfenac can penetrate into the retinochoroidal tissues in high enough concentrations to inhibit COX-2 and exerts its inhibitory effect on the blood-retinal barrier breakdown in an experimental retino choroidal inflammation in rabbits.
Immunomodulatory Effect of Gatifloxacin on Mouse Peritoneal Macrophages in vitro and in Models of Endotoxin-Induced Rat Conjunctivitis and Rabbit Bacterial Keratitis
TL;DR: Results indicate that gatifloxacin has not only antibacterial activity but an anti-inflammatory action caused by at least inhibiting TNF-α production at the doses used in topical ophthalmic therapy.
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Polylactic acid for visualizing the vitreous body during vitrectomy.
Toshifumi Yamashita,Taiji Sakamoto,Keita Yamakiri,Muneki Miura,Hiroshi Enaida,Akifumi Ueno,Ikuyo Atsumi,Keiichi Matsuhisa,Y. Sakamoto,Tetsuo Kida,Tatsuro Ishibashi +10 more
TL;DR: PLA can be a new surgical adjuvant to visualize the vitreous body during vitrectomy and was well visualized in monkey eyes, and the posterior vitreOUS separation was performed easily and safely.
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Effect of dosing interval on the efficacy of topical ophthalmic gatifloxacin against Enterococcus faecalis in an in vitro pharmacokinetic model simulating the local eye compartment.
TL;DR: The relationship between dosing interval and antibacterial efficacy in an in vitro PK model mimicking post-operative endophthalmitis is investigated and the antimicrobial efficacy appears to be associated with the cumulative time of a 24-h period such that the concentration exceeds the minimum inhibitory concentration (T>MIC) rather than the peak concentration:MIC ratio.
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