2003-예방원년, 소아과 의사의 역할

Nanocomposite hydrogel biomaterials represent an exciting Frontier in biomedicine, offering solutions to longstanding challenges. These hydrogels are derived from various biopolymers, including fibrin, silk fibroin, collagen, keratin, gelatin, chitosan, hyaluronic acid, alginate, carrageenan, and cellulose. While these biopolymers possess inherent biocompatibility and renewability, they often suffer from poor mechanical properties and rapid degradation. Researchers have integrated biopolymers such as cellulose, starch, and chitosan into hydrogel matrices to overcome these limitations, resulting in nanocomposite hydrogels. These innovative materials exhibit enhanced mechanical strength, improved biocompatibility, and the ability to finely tune drug release profiles. The marriage of nanotechnology and hydrogel chemistry empowers precise control over these materials' physical and chemical properties, making them ideal for tissue engineering, drug delivery, wound healing, and biosensing applications. Recent advancements in the design, fabrication, and characterization of biopolymer-based nanocomposite hydrogels have showcased their potential to transform biomedicine. Researchers are employing strategic approaches for integrating biopolymer nanoparticles, exploring how nanoparticle properties impact hydrogel performance, and utilizing various characterization techniques to evaluate structure and functionality. Moreover, the diverse biomedical applications of these nanocomposite hydrogels hold promise for improving patient outcomes and addressing unmet clinical needs.

Revolutionizing biomedicine: advancements, applications, and prospects of nanocomposite macromolecular carbohydrate-based hydrogel biomaterials: a review

Bamboo-based magnetic activated carbon for efficient removal of sulfadiazine: Application and adsorption mechanism.

In this study, we employed a straightforward in-situ synthesis strategy to fabricate multi-site adsorption functional composites known as aminated chitosan@ZIF-8 (AmCs@ZIF-8) for the efficient removal of Cu(II) and Congo red. The AmCs@ZIF-8 adsorbed Cu(II) at pH 5 and Congo red at pH 3 with excellent removal efficiency values of 94 % and 100 % respectively. The maximum adsorption capacity for Cu(II) and Congo red are obtained as 785 mg g−1 and 1156 mg g−1, respectively. Interestingly, AmCs@ZIF-8 composites exhibited an excellent removal efficiency (>80 %) after reusing them for four sequential cycles. Analysis of the adsorption isotherm and kinetic data indicated that chemisorption primarily governed the adsorption of Cu(II) and Congo red by AmCs@ZIF-8. Furthermore, we elucidated the adsorption energy of Cu(II) and Congo red on the AmCs@ZIF-8 composite through density functional theory. Specifically, the adsorption energy values for Cu(II) with AmCs and ZIF-8 were −20.907 and −57.809 kcal·mol−1, and −26.514 and −16.242 kcal·mol−1 for Congo red, respectively. The efficient adsorption mechanism of Cu(II) and Congo red on the AmCs@ZIF-8 composite can be attributed to the synergistic effects of chelation, electrostatic attraction, ion exchange, and hydrogen bonding through the analysis of experimental characterization and theoretical calculation. Therefore, AmCs@ZIF-8 composites elevate the adsorption capacity of Cu(II) and Congo red in a single-component system and exhibit high removal efficiency (>90 %) in the context of the Cu(II)-Congo red binary system. 

Composite adsorbents of aminated chitosan @ZIF-8 MOF for simultaneous efficient removal of Cu(II) and Congo Red: Batch experiments and DFT calculations

A novel concept of developing multi-principal elements, or compositional complex alloys is referred as high-entropy alloys (HEAs). This review addresses the role of entropy in alloying additions along with the effect of various elements listed in the periodic table in forming the HEAs. Phase formation rules and the associated parameters along with their significance are discussed. The physical metallurgy technique is elaborated with reference to the high-entropy effect, severe lattice distortion effect, sluggish diffusion effect, and cocktail effects. Various types of HEAs such as light weight HEAs, nanoprecipitate HEAs, ultrafine-grained HEAs, dual-phase HEAS and TRIP/TWIN HEAs are discussed. Further, the effects of mechanical alloying in HEAs are presented. Finally, the microstructural effects and mechanical properties of HEAs are addressed with reference to the published literature. 

Development of high entropy alloys (HEAs): Current trends

A highly efficient biomass-based adsorbent fabricated by graft copolymerization: Kinetics, isotherms, mechanism and coadsorption investigations for cationic dye and heavy metal.

Biomaterial implantation into the human body plays a key role in the medical field and biological applications. Increasing the life expectancy of biomaterial implants, reducing the rejection reaction inside the human body and reducing the risk of infection are the problems in this field that need to be solved urgently. The surface modification of biomaterials can change the original physical, chemical and biological properties and improve the function of materials. This review focuses on the application of surface modification techniques in various fields of biomaterials reported in the past few years. The surface modification techniques include film and coating synthesis, covalent grafting, self-assembled monolayers (SAMs), plasma surface modification and other strategies. First, a brief introduction to these surface modification techniques for biomaterials is given. Subsequently, the review focuses on how these techniques change the properties of biomaterials, and evaluates the effects of modification on the cytocompatibility, antibacterial, antifouling and surface hydrophobic properties of biomaterials. In addition, the implications for the design of biomaterials with different functions are discussed. Finally, based on this review, it is expected that the biomaterials have development prospects in the medical field.

Surface modifications of biomaterials in different applied fields

Adsorption and oxidation of ciprofloxacin by a novel layered double hydroxides modified sludge biochar.

Dye degradation is a key reaction in organic decomposition production through electron donor transferring. Palladium (Pd) is the best-known element for synthesis Pd-based catalyst, the surface status determines the scope of relative applications. Here we first prepare Pd-Cu alloy nanoparticles (NPs) by co-reduction of Cu(acac)2 (acac = acetylacetonate) and Pd(C5HF6O2)2 in the presence of sodium borohydride (NaBH4) and glutathione (GSH). The obtained Pd-Cu is about ~10 nm with super-hydrophilicity in aqueous mediums. The structural analysis clearly demonstrated the uniform distribution of Pd and Cu element. The colloidal solution keeps stability even during 30 days. Bimetallic Pd-Cu NPs shows biocompatibility in form of cell lines (IMEF, HACAT, and 239 T) exposed to colloidal solution (50 µg mL−1) for 2 days. It shows the catalytic multi-performance for dye degradation such as methyl orange (MO), rhodamine B (RhB), and methylene blue (MB), respectively. The as-synthesized nanoparticles showed one of the best multiple catalytic activities in the industrially important (electro)-catalytic reduction of 4-nitrophenol (4-NP) to corresponding amines with noticeable reduced reaction time and increased rate constant without the use of any large area support. In addition, it exhibits peroxidase-like activity in the 3, 3′, 5, 5′-Tetramethylbenzidine (TMB) color test and exhibit obvious difference with previous individual metal materials. By treated with high intensity focused ultrasound filed (HIFU), Pd-Cu NPs might be recrystallized and decreased the diameters than before. The enhancement in catalytic performance is observed obviously. This work expedites rational design and synthesis of the high-hierarchy alloy catalyst for biological and environment-friendly agents.

/pdf/bioinspired-pd-cu-alloy-nanoparticles-as-accept-agent-for-eb312qjn.pdf

Bioinspired Pd-Cu Alloy Nanoparticles as Accept Agent for Dye Degradation Performances

In this work, we firstly report the preparation of heterogeneously assembled structures Au-Ag nanoclusters (NCs) as good drug carriers with high loading performance and biocompatible capability. As glutathione-protected Au and Ag clusters self-assembled into porous Au-Ag NCs, the size value is about 1.358 (±0.05) nm. The morphology characterization revealed that the diameter of Au-Ag NCs is approximately 120 nm, as well as the corresponding potential ability in loading performance of the metal cluster triggered-assembling process. Compared with individual components, the stability and loading performance of heterogeneous Au-Ag NCs were improved and exhibit that the relative biocompatibility was enhanced. The exact information about this is that cell viability was approximately to 98% when cells were incubated with 100 µg mL−1 particle solution for 3 days. The drug release of Adriamycin from Au-Ag NCs was carried out in PBS at pH = 7.4 and 5.8, respectively. By simulating in vivo and tumor microenvironment, the release efficiency could reach over 65% at pH = 5.8 but less than 30% at pH = 7.2. Using an ultrasound field as external environment can accelerate the assembling process while metal clusters triggered assembling Au-Ag NCs. The size and morphology of the assembled Au-Ag NCs can be controlled by using different power parameters (8 W, 13 W, 18 W) under ambient atmosphere. Overall, a novel approach is exhibited, which conveys assembling work for metal clusters triggers into heterogeneous structures with porous characteristic. Its existing properties such as water-solubility, stability, low toxicity and capsulation can be considered as dependable agents in various biomedical applications and drug carriers in immunotherapies.

https://www.mdpi.com/1422-0067/23/19/11197/pdf?version=1663925264

Metal Cluster Triggered-Assembling Heterogeneous Au-Ag Nanoclusters with Highly Loading Performance and Biocompatible Capability

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Teng Wang

Author Tools

Chat about Author