Tatsushi Muta
Kyushu University
13 Papers
197 Citations
Tatsushi Muta is an academic researcher from Kyushu University. The author has contributed to research in topics: Tachypleus tridentatus & Innate immune system. The author has an hindex of 11, co-authored 13 publications.
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Papers
Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.
Soutaro Gokudan,Tatsushi Muta,Ryoko Tsuda,Kumiko Koori,Takeshi Kawahara,Noriaki Seki,Yoshimitsu Mizunoe,Sun Nyunt Wai,Sadaaki Iwanaga,Shun Ichiro Kawabata +9 more
TL;DR: The observations clearly show that the horseshoe crab has fibrinogen-related molecules in hemolymph plasma and that they function as nonself-recognizing lectins.
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•Journal Article
Pulmonary Surfactant Protein A Modulates the Cellular Response to Smooth and Rough Lipopolysaccharides by Interaction with CD14
TL;DR: The results demonstrate the different actions of SP-A upon distinct serotypes of LPS and indicate that the direct interaction ofSP-A with CD14 constitutes a likely mechanism by which SP- A modulates LPS-elicited cellular responses.
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Clotting and immune defense in Limulidae.
Tatsushi Muta,Sadaaki Iwanaga +1 more
TL;DR: A novel heterodimeric serine protease zymogen, factor G, may open a new way to develop an innovative assay system to quantitate beta-(1,3) glucans, which could be utilized as a unique tool to analyze other biological reactions caused by LPS or the glucan.
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Horseshoe crab coagulogen is an invertebrate protein with a nerve growth factor-like domain
TL;DR: The putative structural similarity of coagulogen and the Drosophila morphogen Spaetzle as well as the homology of its processing proteinases suggests a common origin of the two functionally different cascades.
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Head-to-Tail Polymerization of Coagulin, a Clottable Protein of the Horseshoe Crab
Hiroko Kawasaki,Takeru Nose,Tatsushi Muta,Sadaaki Iwanaga,Yasuyuki Shimohigashi,Shun Ichiro Kawabata +5 more
TL;DR: Results indicated that the polymerization of coagulin proceeds through the interaction between the newly exposedHydrophobic cove on the head and the wedge-shaped hydrophobic tail.
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