Tatiana Benavides Damm
Lucerne University of Applied Sciences and Arts
7 Papers
Tatiana Benavides Damm is an academic researcher from Lucerne University of Applied Sciences and Arts. The author has contributed to research in topics: Myocyte & Muscle atrophy. The author has an hindex of 6, co-authored 7 publications. Previous affiliations of Tatiana Benavides Damm include ETH Zurich & Children's Medical Research Institute.
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Papers
Calcium's Role in Mechanotransduction during Muscle Development
TL;DR: How diverse mechanical stimuli cause changes in calcium homeostasis by affecting membrane channels and the intracellular stores, which in turn regulate multiple pathways that impart these effects and control the fate of muscle tissue is discussed in detail.
Calcium-dependent deceleration of the cell cycle in muscle cells by simulated microgravity
Tatiana Benavides Damm,Stéphane Richard,Samuel Tanner,Fabienne Wyss,Marcel Egli,Alfredo Franco-Obregón +5 more
TL;DR: Calcium‐dependent deceleration of the cell cycle in muscle cells by simulated microgravity and a decrease in TRPC1‐mediated calcium entry appears to be a pivotal event in the muscle atrophy brought on by gravitational mechanical unloading.
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Impedance flow cytometry gauges proliferative capacity by detecting TRPC1 expression.
Sara Crocetti,Christian Beyer,Silvio Unternährer,Tatiana Benavides Damm,Tatiana Benavides Damm,Grit Schade-Kampmann,Monika Hebeisen,Marco Di Berardino,Jürg Fröhlich,Alfredo Franco-Obregón,Alfredo Franco-Obregón +10 more
TL;DR: It is shown that a microfluidic configuration of impedance‐based flow cytometry (IFC) provides a method to detect TRP channel expression in cells at high throughput and has the potential to identify living stem cells in their earliest stages of expansion without staining or chemical fixation.
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Gravitational force modulates G2/M phase exit in mechanically unloaded myoblasts.
TL;DR: The results show that SM and HG exert phenomenological distinct responses over cell cycle progression, whereas the effects of HG are indistinguishable from the 1 g control, suggesting that the mechanotransduction apparatus of cells responds differently to mechanical unloading and loading.
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Ground-based study of gravitational forces acting on muscle cells
Tatiana Benavides Damm
- 01 Jan 2014
TL;DR: The key calcium-dependent pathways described here include the nuclear factor of activated T cells (NFAT) and mitogen-activated protein kinase (MAPK) activation, which lead to a cascade of events by the activation of downstream signaling pathways, all necessary for healthy muscle development.