Tammy E. Hedlund
Anschutz Medical Campus
15 Papers
504 Citations
Tammy E. Hedlund is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Receptor & LNCaP. The author has an hindex of 14, co-authored 15 publications.
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Papers
The Metabolites Citrate, Myo-Inositol, and Spermine Are Potential Age-Independent Markers of Prostate Cancer in Human Expressed Prostatic Secretions
Natalie J. Serkova,Eduard J. Gamito,Richard H. Jones,Colin O'Donnell,Jaimi L. Brown,Spencer Green,Holly T. Sullivan,Tammy E. Hedlund,E. David Crawford +8 more
TL;DR: Proton nuclear magnetic resonance spectroscopy (1H‐NMRS) is used to assess potential metabolic markers of prostate cancer (PCa) in human expressed prostatic secretions (EPS) in this study.
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Stable expression of the nuclear vitamin D receptor in the human prostatic carcinoma cell line JCA-1: evidence that the antiproliferative effects of 1 alpha, 25-dihydroxyvitamin D3 are mediated exclusively through the genomic signaling pathway.
TL;DR: Because the stereoisomer 1 beta, 25-dihydroxyvitamin D3 failed to block these antiproliferative effects, it is concluded that nongenomic mechanisms of action are not requisite for growth inhibition by 1,25-(OH)2D3.
Long-Term Dietary Habits Affect Soy Isoflavone Metabolism and Accumulation in Prostatic Fluid in Caucasian Men
Tammy E. Hedlund,Paul Maroni,Paul G. Ferucci,Robert Dayton,Stephen Barnes,Kenneth Jones,Ray Moore,Lorraine G. Ogden,Kristiina Wähälä,Holly M Sackett,Karen J Gray +10 more
TL;DR: The data suggest that the ability of Caucasian men to produce equol is favorably influenced by the long-term consumption of high amounts of soy and the consumption of meat.
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Vitamin D receptor expression is required for growth modulation by 1α,25-dihydroxyvitamin D3 in the human prostatic carcinoma cell line ALVA-31
TL;DR: It is concluded that the antiproliferative effects of 1,25(OH)2 D3 require expression of the nuclear VDR in this system, and an active role for the nuclear vitamin D receptor (VDR) in mediating the growth-inhibitory effects of this substance is provided.
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Fas‐mediated apoptosis in seven human prostate cancer cell lines: Correlation with tumor stage
TL;DR: The role of Fas‐signaling in the human prostate, and if this signaling pathway is abrogated in the development of prostate cancer (PC), is investigated.
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