Takuya Yokoi
Osaka City University
33 Papers
7 Citations
Takuya Yokoi is an academic researcher from Osaka City University. The author has contributed to research in topics: Medicine & Nerve guidance conduit. The author has an hindex of 6, co-authored 20 publications.
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Papers
Protective effect of biodegradable nerve conduit against peripheral nerve adhesion after neurolysis.
Kosuke Shintani,Takuya Uemura,Kiyohito Takamatsu,Takuya Yokoi,Ema Onode,Mitsuhiro Okada,Hiroaki Nakamura +6 more
TL;DR: The nerve conduit prevented post-neurolysis peripheral nerves from developing adhesion and allowed them to maintain their nerve function because it effectively blocked scarring and prevented adhesion-related damage in the peripheral nerves.
Long-Term Efficacy and Safety Outcomes of Transplantation of Induced Pluripotent Stem Cell-Derived Neurospheres with Bioabsorbable Nerve Conduits for Peripheral Nerve Regeneration in Mice
Takuya Uemura,Mikinori Ikeda,Kiyohito Takamatsu,Takuya Yokoi,Mitsuhiro Okada,Hiroaki Nakamura +5 more
TL;DR: It is demonstrated that bioabsorbable nerve conduits coated with iPSc-derived neurospheres promote enhanced regeneration of peripheral nerves and functional recovery without teratoma formation in the long term.
33
Nerve capping with a nerve conduit for the treatment of painful neuroma in the rat sciatic nerve.
Ema Onode,Takuya Uemura,Takuya Uemura,Kiyohito Takamatsu,Kosuke Shintani,Takuya Yokoi,Mitsuhiro Okada,Hiroaki Nakamura +7 more
TL;DR: In the rat sciatic nerve amputation model, nerve capping treatment with a bioabsorbable nerve conduit provided relief from neuroma-induced neuropathic pain and prevented perineural scar formation and neuroinflammation around the nerve stump.
31
Bioabsorbable nerve conduits three-dimensionally coated with human induced pluripotent stem cell-derived neural stem/progenitor cells promote peripheral nerve regeneration in rats
Ema Onode,Takuya Uemura,Takuya Uemura,Kiyohito Takamatsu,Takuya Yokoi,Kosuke Shintani,Shunpei Hama,Yusuke Miyashima,Mitsuhiro Okada,Hiroaki Nakamura +9 more
TL;DR: In this paper, a tissue-engineered nerve conduit coated with mouse induced pluripotent stem cell (iPSC)-derived neurospheres was developed for the first time, which accelerated nerve regeneration in mice.
Bioabsorbable nerve conduits coated with induced pluripotent stem cell-derived neurospheres enhance axonal regeneration in sciatic nerve defects in aged mice.
Takuya Yokoi,Takuya Uemura,Kiyohito Takamatsu,Kosuke Shintani,Ema Onode,Mitsuhiro Okada,Noriaki Hidaka,Hiroaki Nakamura +7 more
TL;DR: It is proposed that tissue-engineered bioabsorbable nerve conduits in combination with mouse induced pluripotent stem cell (iPSc)-derived neurospheres hold therapeutic potential both in young and elderly patients.