Takuya Uemura
West Japan Railway Company
61 Papers
112 Citations
Takuya Uemura is an academic researcher from West Japan Railway Company. The author has contributed to research in topics: Medicine & Nerve guidance conduit. The author has an hindex of 11, co-authored 53 publications. Previous affiliations of Takuya Uemura include Osaka City University.
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Papers
Acceleration of peripheral nerve regeneration using nerve conduits in combination with induced pluripotent stem cell technology and a basic fibroblast growth factor drug delivery system
Mikinori Ikeda,Takuya Uemura,Kiyohito Takamatsu,Mitsuhiro Okada,Kenichi Kazuki,Yasuhiko Tabata,Yoshito Ikada,Hiroaki Nakamura +7 more
TL;DR: The combination of all three fundamental methodologies, iPSc technology for supportive cells, bioabsorbable nerve conduits for scaffolds, and a bFGF drug delivery system for growth factors, was essential for peripheral nerve regenerative therapy.
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Transplantation of induced pluripotent stem cell-derived neurospheres for peripheral nerve repair.
Takuya Uemura,Kiyohito Takamatsu,Mikinori Ikeda,Mitsuhiro Okada,Kenichi Kazuki,Yoshito Ikada,Hiroaki Nakamura +6 more
TL;DR: The bioabsorbable nerve conduits created by 3D-culture of iPS cell-derived neurospheres promoted regeneration of peripheral nerves and functional recovery in vivo.
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Protective effect of biodegradable nerve conduit against peripheral nerve adhesion after neurolysis.
Kosuke Shintani,Takuya Uemura,Kiyohito Takamatsu,Takuya Yokoi,Ema Onode,Mitsuhiro Okada,Hiroaki Nakamura +6 more
TL;DR: The nerve conduit prevented post-neurolysis peripheral nerves from developing adhesion and allowed them to maintain their nerve function because it effectively blocked scarring and prevented adhesion-related damage in the peripheral nerves.
Long-Term Efficacy and Safety Outcomes of Transplantation of Induced Pluripotent Stem Cell-Derived Neurospheres with Bioabsorbable Nerve Conduits for Peripheral Nerve Regeneration in Mice
Takuya Uemura,Mikinori Ikeda,Kiyohito Takamatsu,Takuya Yokoi,Mitsuhiro Okada,Hiroaki Nakamura +5 more
TL;DR: It is demonstrated that bioabsorbable nerve conduits coated with iPSc-derived neurospheres promote enhanced regeneration of peripheral nerves and functional recovery without teratoma formation in the long term.
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Nerve capping with a nerve conduit for the treatment of painful neuroma in the rat sciatic nerve.
Ema Onode,Takuya Uemura,Takuya Uemura,Kiyohito Takamatsu,Kosuke Shintani,Takuya Yokoi,Mitsuhiro Okada,Hiroaki Nakamura +7 more
TL;DR: In the rat sciatic nerve amputation model, nerve capping treatment with a bioabsorbable nerve conduit provided relief from neuroma-induced neuropathic pain and prevented perineural scar formation and neuroinflammation around the nerve stump.
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