Takuma Yamashita
Kagawa University
5 Papers
2 Citations
Takuma Yamashita is an academic researcher from Kagawa University. The author has contributed to research in topics: Cell cycle & Metformin. The author has an hindex of 4, co-authored 5 publications.
Chat about Author
Papers
Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies
Takayuki Fujimori,Kiyohito Kato,Shintaro Fujihara,Hisakazu Iwama,Takuma Yamashita,Kiyoyuki Kobayashi,Hideki Kamada,Asahiro Morishita,Hideki Kobara,Hirohito Mori,Keiichi Okano,Yasuyuki Suzuki,Tsutomu Masaki +12 more
TL;DR: Findings suggest that metformin may have clinical use in the treatment of CCA, and identify the microRNAs associated with its antitumor effects.
Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest.
Kiyoyuki Kobayashi,Asahiro Morishita,Hisakazu Iwama,Koji Fujita,Ryoichi Okura,Shintaro Fujihara,Takuma Yamashita,Takayuki Fujimori,Kiyohito Kato,Hideki Kamada,Toshiro Niki,Mitsuomi Hirashima,Keiichi Okano,Yasuyuki Suzuki,Tsutomu Masaki +14 more
TL;DR: Gal-9 can be a candidate of therapeutic target in the treatment of cholangiocarcinoma as well as the microRNAs (miRNAs) associated with the antitumor effects of Gal-9.
The anti-diabetic drug metformin inhibits pancreatic cancer cell proliferation in vitro and in vivo: Study of the microRNAs associated with the antitumor effect of metformin.
Kiyohito Kato,Hisakazu Iwama,Takuma Yamashita,Kiyoyuki Kobayashi,Shintaro Fujihara,Takayuki Fujimori,Hideki Kamada,Hideki Kobara,Tsutomu Masaki +8 more
TL;DR: The results revealed that metformin inhibits human pancreatic cancer cell proliferation and tumor growth, possibly by suppressing the cell cycle-related molecules via alteration of miRNAs.
Anti-diabetic drug metformin inhibits cell proliferation and tumor growth in gallbladder cancer via G0/G1 cell cycle arrest.
Takuma Yamashita,Kiyohito Kato,Shintaro Fujihara,Hisakazu Iwama,Asahiro Morishita,Hiroki Yamana,Kiyoyuki Kobayashi,Hideki Kamada,Taiga Chiyo,Hideki Kobara,Kunihiko Tsutsui,Keiichi Okano,Yasuyuki Suzuki,Tsutomu Masaki +13 more
TL;DR: The results suggest that metformin may be used clinically for the treatment of gallbladder adenocarcinoma, and markedly altered microRNA expression profile leading to an anti-tumor effect.
16
Long-Term Management of Recurrent Cholecystitis after Initial Conservative Treatment: Endoscopic Transpapillary Gallbladder Stenting.
Hideki Kamada,Hideki Kobara,Naohito Uchida,Kiyohito Kato,Takayuki Fujimori,Kiyoyuki Kobayashi,Takuma Yamashita,Masahiro Ono,Yuichi Aritomo,Kunihiko Tsutsui,Keiichi Okano,Yasuyuki Suzuki,Tsutomu Masaki +12 more
TL;DR: Endoscopic transpapillary gallbladder stenting is an effective alternative for managing RC in high-risk patients with severe comorbidities in patients for whom cholecystectomy is contraindicated because of its high surgical risk.