Takeshi Oguchi
Nagoya University
38 Papers
279 Citations
Takeshi Oguchi is an academic researcher from Nagoya University. The author has contributed to research in topics: Rheumatoid arthritis & Medicine. The author has an hindex of 12, co-authored 31 publications.
Chat about Author
Papers
Depression, inflammation, and pain in patients with rheumatoid arthritis.
Masayo Kojima,Toshihisa Kojima,Sadao Suzuki,Takeshi Oguchi,Michinari Oba,Hiroki Tsuchiya,Fumiaki Sugiura,Yasuhide Kanayama,Toshiaki A. Furukawa,Shinkan Tokudome,Naoki Ishiguro +10 more
TL;DR: Depression severity and inflammation were associated with each other and appeared to have independent effects on perceived pain, suggesting a clinical approach that takes into account both the body and the mind could have benefits and could enable optimal pain control.
223
Psychosocial factors, disease status, and quality of life in patients with rheumatoid arthritis
Masayo Kojima,Toshihisa Kojima,Naoki Ishiguro,Takeshi Oguchi,Michinari Oba,Hiroki Tsuchiya,Fumiaki Sugiura,Toshiaki A. Furukawa,Sadao Suzuki,Shinkan Tokudome +9 more
TL;DR: Clinicians should evaluate psychosocial factors, as well as subjective disease status, to improve the QOL of patients with RA.
121
Relationships of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover and inflammation as revealed by analyses of synovial fluids from patients with rheumatoid arthritis.
Naoki Ishiguro,Takayasu Ito,Takeshi Oguchi,Toshihisa Kojima,Hisashi Iwata,Mirela Ionescu,A. Robin Poole +6 more
TL;DR: The observations provide new insights into the complex changes in cartilage turnover and PMN influx in RA joints and suggest that HA and PMNs may be involved in the control of proteolysis and cartilage proteoglycan assembly.
89
Differential Stimulation of Three Forms of Hyaluronan Synthase by TGF-β, IL-1β, and TNF-α
Takeshi Oguchi,Naoki Ishiguro +1 more
TL;DR: Differences in the expression pattern of HAS1, HAS2, and HAS3 mRNA by cytokines suggest that these three isoforms are independently and differentially regulated, and each isoform of HAS may have a different role in arthritic joint disease.
50
Study protocol of a multicenter registry of patients with rheumatoid arthritis starting biologic therapy in Japan : Tsurumai Biologics Communication Registry (TBCR) Study
Toshihisa Kojima,Atsushi Kaneko,Yuji Hirano,Hisato Ishikawa,Hiroyuki Miyake,Takeshi Oguchi,Hideki Takagi,Yuichiro Yabe,Takefumi Kato,Takayasu Ito,Kenya Terabe,Naoki Fukaya,Yasuhide Kanayama,Tomone Shioura,Koji Funahashi,Masatoshi Hayashi,Daizo Kato,H. Matsubara,Takayoshi Fujibayashi,Masayo Kojima,Naoki Ishiguro +20 more
TL;DR: Differences in baseline characteristics by age and initiation year of biologics need to be carefully evaluated in order to report on drug-related survival and long-term prognosis, using follow-up data in the near future.
37