Takeo Hara
Osaka University
25 Papers
78 Citations
Takeo Hara is an academic researcher from Osaka University. The author has contributed to research in topics: Medicine & Eosinophilic esophagitis. The author has an hindex of 6, co-authored 16 publications. Previous affiliations of Takeo Hara include Children's Hospital of Philadelphia & University of Pennsylvania.
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Papers
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.
Takashi Kijima,Hiroshi Nakagawa,Masataka Shimonosono,Prasanna M. Chandramouleeswaran,Takeo Hara,Varun Sahu,Yuta Kasagi,Osamu Kikuchi,Koji Tanaka,Veronique Giroux,Amanda B. Muir,Kelly A. Whelan,Shinya Ohashi,Seiji Naganuma,Andres J. Klein-Szanto,Yoshiaki Shinden,Ken Sasaki,Itaru Omoto,Yoshiaki Kita,Manabu Muto,Adam J. Bass,J. Alan Diehl,Gregory G. Ginsberg,Yuichiro Doki,Masaki Mori,Yasuto Uchikado,Takaaki Arigami,Narayan G. Avadhani,Devraj Basu,Anil K. Rustgi,Shoji Natsugoe +30 more
TL;DR: The single cell-based 3D organoid system may serve as a highly efficient platform to explore cancer therapeutics and therapy resistance mechanisms in conjunction with morphological and functional assays with implications for translation in personalized medicine.
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CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis
Takeo Hara,Yuta Kasagi,Joshua X. Wang,Masaru Sasaki,Bailey Aaron,Adam L. Karami,Masataka Shimonosono,Rieko Shimonosono,Hisatsugu Maekawa,Lauren Dolinsky,Benjamin J. Wilkins,Jeremy Klein,Jane M Wei,Kathryn Nunes,Kristle L. Lynch,Jonathan M. Spergel,Kathryn E. Hamilton,Melanie A. Ruffner,Tatiana A. Karakasheva,Kelly A. Whelan,Hiroshi Nakagawa,Amanda B. Muir +21 more
TL;DR: In this article , the authors investigated the role of CD73+CD104+ cells in epithelial renewal and homeostasis in the context of eosinophilic esophagitis.
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Very High-Energy Gamma-Ray Observations of PSR B1509-58 with the CANGAROO 3.8m Telescope
T. K. Sako,Yutaka Matsubara,Y. Muraki,P. V. Ramanamurthy,S. A. Dazeley,P. G. Edwards,S. Gunji,Takeo Hara,S. Hara,Jamie Holder,S. Kamei,Akiko Kawachi,Tadashi Kifune,R. Kita,Akira Masaike,Yoshihiko Mizumoto,Masaki Mori,M. Moriya,Hiroshi Muraishi,Tsuguya Naito,K. Nishijima,S. Ogio,J. R. Patterson,Gavin Rowell,K. Sakurazawa,Y. Sato,R. Susukita,R. Suzuki,T. Tamura,Toru Tanimori,G. J. Thornton,Shohei Yanagita,Tetsuya Yoshida,Takanori Yoshikoshi +33 more
TL;DR: The gamma-ray pulsar PSR B1509-58 and its surrounding nebulae have been observed with the CANGAROO 3.8m imaging atmospheric Cherenkov telescope.
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Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids.
Hiroshi Nakagawa,Yuta Kasagi,Yuta Kasagi,Tatiana A. Karakasheva,Tatiana A. Karakasheva,Takeo Hara,Takeo Hara,Bailey Aaron,Bailey Aaron,Masataka Shimonosono,Takashi Kijima,Veronique Giroux,Dominique Bailey,Benjamin J. Wilkins,Julian A. Abrams,Gary W. Falk,Seema S. Aceves,Jonathan M. Spergel,Jonathan M. Spergel,Kathryn E. Hamilton,Kathryn E. Hamilton,Kelly A. Whelan,Amanda B. Muir,Amanda B. Muir +23 more
TL;DR: The protocols for rapid generation and characterization of single-cell-derived, three-dimensional (3D) esophageal organoids from human subjects and mice with normal esophagal mucosa or inflammatory disease conditions are described.
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Comparison of short-term outcomes between 2- and 3-field lymph node dissection for esophageal cancer.
Kotaro Yamashita,Tomoki Makino,Makoto Yamasaki,K. Tanaka,Takeo Hara,Yasuaki Miyazaki,Tsuyoshi Takahashi,Yukinori Kurokawa,Kiyokazu Nakajima,S. Takiguchi,Masaki Mori,Y. Doki +11 more
TL;DR: 3- FLD could be as feasible as 2-FLD in ESCC patients in terms of short-term outcome and postoperative complications, and the field of lymphadenectomy negatively impacted the short- term outcome in ES CC patients in Terms of pneumonia and inflammatory response.
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