Takehiro Yamagishi
Taisho Pharmaceutical Co.
41 Papers
467 Citations
Takehiro Yamagishi is an academic researcher from Taisho Pharmaceutical Co.. The author has contributed to research in topics: Enantioselective synthesis & Chirality (chemistry). The author has an hindex of 15, co-authored 41 publications. Previous affiliations of Takehiro Yamagishi include University of Tokyo & Tokyo University of Pharmacy and Life Sciences.
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Papers
Patent
Cyclic hexapeptide compounds
Hideji Itokawa,Y. Hitotsuyanagi,Takehiro Yamagishi +2 more
- 10 Sep 1996
TL;DR: In this paper, a general formula for cyclic hexapeptide compounds having an excellent drug effect was proposed, where n is an integer of from 4 to 6 and n is the number of amino acid residues.
1
Patent
Substituted benzoic acid derivative
Hisaya Wada,Hajime Asanuma,Tetsuo Takayama,Masakazu Sato,Takehiro Yamagishi,Shibuya Masashi +5 more
- 10 Jul 2002
TL;DR: In this article, the problem of providing a compound used as a VEGF receptor antagonist for the treatment of diseases which the vascularization induced by VEGFs participates in and the improvement of morbid symptoms induced by the VEGFL was addressed.
1
Reductive Alkylation of Hydrazine Derivatives with α-Picoline-Borane and Its Applications to the Syntheses of Useful Compounds Related to Active Pharmaceutical Ingredients.
Yasushi Kawase,Takehiro Yamagishi,Jun-ya Kato,Teruo Kutsuma,Tadashi Kataoka,Takeo Iwakuma,Tsutomu Yokomatsu +6 more
TL;DR: This method was successfully applied in the synthesis of compound (XV) as discussed by the authors, an important segment of atazanavir, and was applied to synthesize compound(XV).
Mechanism of action of aragusterol a (YTA0040), a potent anti‐tumor marine steroid targeting the G1 phase of the cell cycle
Kazuya Fukuoka,Takehiro Yamagishi,Tomoko Ichihara,Shiro Nakaike,Kazuo Iguchi,Yasuji Yamada,Hisao Fukumoto,Takahiro Yoneda,Kazunori Samata,Hisao Ikeya,Kayoko Nanaumi,Noriko Hirayama,Nobuhiro Narita,Nagahiro Saijo,Kazuto Nishio +14 more
TL;DR: Findings indicated that YTA0040 arrested human NSCLC cells in late G1 phase of the cell cycle through inhibition of pRb phosphorylation.
Reductive Alkylation of Hydrazine Derivatives with α-Picoline-Borane and Its Applications to the Syntheses of Useful Compounds Related to Active Pharmaceutical Ingredients
Yasushi Kawase,Takehiro Yamagishi,Jun-ya Kato,Teruo Kutsuma,Tadashi Kataoka,Takeo Iwakuma,Tsutomu Yokomatsu +6 more
TL;DR: In this paper, an efficient method for the direct reductive alkylation of hydrazine derivatives with α-picoline-borane has been developed to synthesize a variety of N-alkylhydrazine derivative.