Takehiro Imura
Tohoku University
39 Papers
17 Citations
Takehiro Imura is an academic researcher from Tohoku University. The author has contributed to research in topics: Islet & Transplantation. The author has an hindex of 8, co-authored 22 publications.
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Papers
Collagenase H is crucial for isolation of rat pancreatic islets
Atsushi Fujio,Kazutaka Murayama,Youhei Yamagata,Kimiko Watanabe,Takehiro Imura,Akiko Inagaki,Naomi Ohbayashi,Naomi Ohbayashi,Hiroki Shima,Satoshi Sekiguchi,Keisei Fujimori,Kazuhiko Igarashi,Noriaki Ohuchi,Susumu Satomi,Masafumi Goto +14 more
TL;DR: The present study reveals that ColH is crucial, while ColG plays only a supporting role, in rat islet isolation, in addition, collagen III appears to be one of the key targets of ColH.
36
A novel resting strategy for improving islet engraftment in the liver.
Takuya Jimbo,Akiko Inagaki,Takehiro Imura,Satoshi Sekiguchi,Yasuhiro Nakamura,Keisei Fujimori,Jun-ichiro Miyagawa,Noriaki Ohuchi,Susumu Satomi,Masafumi Goto +9 more
TL;DR: The data suggest that short-term fasting combined with insulin treatment, especially during the avascular period of the grafts, could be a promising regimen for improving pancreatic islet engraftment in the liver.
20
Thioredoxin-1 Attenuates Early Graft Loss after Intraportal Islet Transplantation in Mice
Kengo Asami,Akiko Inagaki,Takehiro Imura,Satoshi Sekiguchi,Keisei Fujimori,Hiroshi Masutani,Junji Yodoi,Junji Yodoi,Susumu Satomi,Noriaki Ohuchi,Masafumi Goto +10 more
TL;DR: The present study demonstrates that overexpression of TRX on the islet grafts is not sufficient to improve engraftment, and proposes that a combination ofTRX and other anti-inflammatory treatments represents a promising regimen for improving the efficacy of islet transplantation.
Ductal injection does not increase the islet yield or function after cold storage in a vascular perfusion model
Wataru Nakanishi,Takehiro Imura,Akiko Inagaki,Yasuhiro Nakamura,Satoshi Sekiguchi,Keisei Fujimori,Susumu Satomi,Masafumi Goto +7 more
TL;DR: It is proposed that ductal injection can be an effective and simple alternative for vascular perfusion prior to pancreas harvest, but is not necessary in most cases, since vascular perfusions are routinely performed.
Decellularized Whole-Organ Pre-vascularization: A Novel Approach for Organogenesis.
TL;DR: In this paper, the axial pre-vascularization approach was used for pancreatic islet transplantation in male Lewis rats, and the decellularized liver scaffold was implanted into Lewis rats and an arteriovenous bundle was passed through the scaffold.