Takashi Takeda

TL;DR: Inhibition at any point in the mevalonate pathway, and especially of farnesyl pyroph phosphate and geranylgeranyl pyrophosphate, suppresses growth of ovarian cancer cells, and the mechanism of the antitumor effect from a metabolic perspective is investigated.

TL;DR: The use of MSI analysis as a predictive biomarker for the therapeutic efficacy of these drugs may be useful for reducing the costs of drug therapy.

TL;DR: Important results have been revealed by genome-wide analyses; however, the pathogenic underlying mechanisms of gynecologic cancer will require further studies and multilateral evaluation using epigenetic, transcriptomic and proteomic analyses, in addition to genomic analysis.

TL;DR: There is an urgent need for researchers to be actively involved in investigator-initiated clinical trials because it is becoming increasingly clear that statins can be effective in the prevention of coronary disease, heart failure, and arrhythmia.