Takashi Shigematsu
Wakayama Medical University
210 Papers
1.6K Citations
Takashi Shigematsu is an academic researcher from Wakayama Medical University. The author has contributed to research in topics: Secondary hyperparathyroidism & Medicine. The author has an hindex of 39, co-authored 202 publications. Previous affiliations of Takashi Shigematsu include Chugai Pharmaceutical Co. & Jikei University School of Medicine.
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Papers
•Journal Article
The role of phosphatonin in phosphate metabolism
TL;DR: FGF-23, which has been detected from TIO tumors, can induce hypophosphatemia by direct inhibition on phosphate reabsorption and by suppressing 1,25 (OH)(2)D(3) production through the inhibition of 25-hydroxyvitaminD 1alpha-hydroxylase, in the kidney.
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Possible prevention of uremic nausea by vitamin D receptor activators in non-dialysis patients with stage 5 chronic kidney disease
Masato Ikeda,Yoshimi Ueda,Yukio Maruyama,Keitaro Yokoyama,Takashi Yokoo,Nobuhiko Joki,Ryoichi Ando,Toshio Shinoda,Daijo Inaguma,Toshihiko Yamaka,Yasuhiro Komatsu,Fumihiko Koiwa,Toshifumi Sakaguchi,Shigeo Negi,Takashi Shigematsu +14 more
TL;DR: Use of VDRAs during the predialysis period was the only factor associated with a lower prevalence of uremic nausea, suggesting that VDRs may prevent uremi nausea in patients with advanced CKD.
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•Journal Article
PTH and bone metabolism in chronic dialysis patients
TL;DR: The abnormal metabolism of calcium and bone is one of the most common complications seen in chronic dialysis patients and accumulated osteoprotegerin in uremic serum may be responsible for this skeletal resistance to PTH.
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Successful non-surgical treatment on bilateral spontaneous perirenal giant hematomas in rapidly progressive glomerulonephritis with MPO-ANCA positive
Yuri Nakashima,Maki Ohura,Toru Mima,Asuka Masumoto,Masaki Ohya,Shigeo Negi,Takashi Shigematsu +6 more
TL;DR: Nephrectomy or embolization is commonly required in patients with perirenal hematoma associated with neoplasm or PN, but radical invasive management may not be necessary in patientswith MPA because smaller blood vessels are affected, resulting in less extensive bleeding and normal clotting.
Lung metastatic calcification in long-term dialysis patients, detected by single photon emission computed tomography (SPECT)
Sayumi Unemura,Yoshindo Kawaguchi,Mayuki Uchiyama,Takashi Shigematsu,Masaaki Nakayama,Tatsuo Hosoya +5 more
TL;DR: Diffuse calcification over the whole lung is considered to be related to a low-turnover bone state concomitant with low PTH level, and L-SPECT is very useful for the early detection of MLC.
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