Taisho Abe
University of Tokyo
3 Papers
Taisho Abe is an academic researcher from University of Tokyo. The author has contributed to research in topics: Ribosome & Chemistry. The author has an hindex of 2, co-authored 3 publications.
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Papers
Reconstitution of yeast translation elongation and termination in vitro utilizing CrPV IRES-containing mRNA
TL;DR: It is found that a high eEF1A concentration relative to the ribosome concentration is critically required for efficient IRes-mediated translation initiation, to ensure its dominance over IRES-independent random internal translation initiation.
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In vitro yeast reconstituted translation system reveals function of eIF5A for synthesis of long polypeptide.
Taisho Abe,Riku Nagai,Shunta Shimazaki,Shunta Kondo,Satoshi Nishimura,Yuriko Sakaguchi,Tsutomu Suzuki,Hiroaki Imataka,Kozo Tomita,Nono Takeuchi-Tomita +9 more
TL;DR: The hypusine-modification drastically stimulates ability of eIF5A to rescue polyproline-mediated ribosome stalling, and is particularly important for the efficient translation of the N-terminal or long internal polypro line-motifs.
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Tight interaction of eEF2 in the presence of Stm1 on ribosome
TL;DR: Stm1 severely inhibits translation through its N-terminal region, and this inhibition is antagonized by eEF3, and it is found that Stm1 stabilizes eEF2 on the 80 S ribosome in the GTP-bound form, independently of e EF2's diphthamide modification, a conserved post-translational modification at the tip of domain IV.