Tai Yang
Chengdu Medical College
16 Papers
35 Citations
Tai Yang is an academic researcher from Chengdu Medical College. The author has contributed to research in topics: Chemistry & T cell. The author has an hindex of 6, co-authored 16 publications.
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Papers
Celastrol induce apoptosis of human multiple myeloma cells involving inhibition of proteasome activity.
Zhong Yueling,Xu Gaojie,Huang Sheng,Li Zhao,Yan Zeng,Xiao-fan Xiao,Jing-lin An,Jin Liu,Tai Yang +8 more
TL;DR: The results reveal the effects of celastrol on proteasome activity in MM cells and shed light on the underlying mechanisms of its anticancer activity, providing a basis for developing Celastrol as a potential therapeutic agent for MM.
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BD750, a benzothiazole derivative, inhibits T cell proliferation by affecting the JAK3/STAT5 signalling pathway.
Yang Liu,Tai Yang,Hongyu Li,Minhui Li,Jin Liu,Yan-Tang Wang,Shu-Xia Yang,Zheng J,Xing-Yan Luo,Yi Lai,Ping Yang,Li-Mei Li,Qiang Zou +12 more
TL;DR: A series of benzothiazole derivatives were screened for Immunosuppressive activity and BD750 was found to be the most effective immunosuppressant.
Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways.
Tai Yang,Jin Liu,Mali Yang,Ning Huang,Zhong Yueling,Ting Zeng,Rong Wei,Wu Zhongjun,Cui Xiao,Cao Xiaohua,Minhui Li,Li-Mei Li,Bin Han,Xiaoping Yu,Hua Li,Qiang Zou +15 more
TL;DR: The results indicate that CuB is a novel inhibitor of Aurora A in multiple myeloma (MM) cells, arresting cells in the G2/M phase, and represents a promising therapeutic tool for the treatment of MM.
Tolerogenic Dendritic Cells Induced by BD750 Ameliorate Proinflammatory T cell Responses and Experimental Autoimmune Encephalitis in Mice
Yan Zhou,Xiao Leng,Hua Li,Shu-Xia Yang,Tai Yang,Li-Mei Li,Ying Xiong,Qiang Zou,Yang Liu,Yan-Tang Wang +9 more
TL;DR: Treatment with BD750 induced tolDC that inhibited proinflammatory T cell immunity in vitro and in vivo and may be valuable for development of new therapies for EAE and other autoimmune diseases.
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Cucurbitacin B exhibits antitumor effects on CD133+ HepG2 liver cancer stem cells by inhibiting JAK2/STAT3 signaling pathway.
Xiaoli Wang,Yudi Bai,Xue Yan,Jin Li,Bingxue Lin,Linzhi Dai,Cheng Xu,Hua Li,Dong Li,Tai Yang,Tao Zhang +10 more
TL;DR: In this paper, the authors investigated the effects of Cucurbitacin B (CuB) on liver cancer stem cells (CSCs) and explored the underlying molecular mechanisms in these liver CSCs.
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