Taehoon Ryu
Seoul National University
36 Papers
31 Citations
Taehoon Ryu is an academic researcher from Seoul National University. The author has contributed to research in topics: Substrate (printing) & Computer data storage. The author has an hindex of 7, co-authored 28 publications.
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Papers
High information capacity DNA-based data storage with augmented encoding characters using degenerate bases.
Yeongjae Choi,Taehoon Ryu,Amos Chungwon Lee,Hansol Choi,Hansaem Lee,Jaejun Park,Suk-Heung Song,Seojoo Kim,H.C. Kim,Wook Park,Sunghoon Kwon +10 more
TL;DR: The use of degenerate bases as encoding characters in addition to A, C, G, and T is proposed, which augments the amount of data that can be stored per length of DNA sequence designed (information capacity) and lowering the amountof DNA synthesis per storing unit data.
DNA Micro-Disks for the Management of DNA-Based Data Storage with Index and Write-Once-Read-Many (WORM) Memory Features.
Yeongjae Choi,Hyung Jong Bae,Amos Chungwon Lee,Hansol Choi,Daewon Lee,Taehoon Ryu,Jinwoo Hyun,Seojoo Kim,H.C. Kim,Suk-Heung Song,Kibeom Kim,Wook Park,Sunghoon Kwon +12 more
TL;DR: DNA micro‐disks, QR‐coded micro‐sized disks that harbor data‐encoded DNA molecules for the efficient management of DNA‐based data storage are proposed, allowing selective and multiple accession of data‐ Encoded DNA with lower data loss than previous DNA‐ based data storage methods.
High-throughput retrieval of physical DNA for NGS-identifiable clones in phage display library.
Jinsung Noh,Okju Kim,Yushin Jung,Haejun Han,Jung-Eun Kim,Soohyun Kim,Sang Hyub， Lee,Jaeseong Park,Rae Hyuck Jung,Sang Il Kim,Jaejun Park,Jerome Han,Hyunho Lee,Duck Kyun Yoo,Amos Chungwon Lee,Euijin Kwon,Taehoon Ryu,Junho Chung,Sunghoon Kwon +18 more
TL;DR: A new high-throughput platform for the identification and retrieval of clones in the library, TrueRepertoire™, which provides highly accurate sequences of the clones with linkage information between heavy and light chains of the antibody fragment.
20
Purification of multiplex oligonucleotide libraries by synthesis and selection.
Hansol Choi,Yeongjae Choi,Yeongjae Choi,Jaewon Choi,Amos Chungwon Lee,Huiran Yeom,Jinwoo Hyun,Taehoon Ryu,Sunghoon Kwon +8 more
TL;DR: In this paper, a length-based method with single-base resolution for purification of complex libraries containing oligos of identical or different lengths was developed, which can be performed either step-by-step manually or using a next-generation sequencer.
19
Barcode-free next-generation sequencing error validation for ultra-rare variant detection
Huiran Yeom,Yonghee Lee,Taehoon Ryu,Jinsung Noh,Amos Chungwon Lee,Han-Byoel Lee,Eunji Kang,Seo Woo Song,Sunghoon Kwon +8 more
TL;DR: A barcode-free NGS error validation method that physically extracts erroneous reads to identify true variants and achieves a PCR-induced error rate of 2.5×10−6 per base per doubling event, using 10 times less sequencing reads compared to those from previous studies.