Tae Gen Son
9 Papers
62 Citations
Tae Gen Son is an academic researcher. The author has contributed to research in topics: Cell growth & Gene silencing. The author has an hindex of 7, co-authored 9 publications.
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Papers
The histone demethylase JMJD1A regulates adrenomedullin-mediated cell proliferation in hepatocellular carcinoma under hypoxia.
TL;DR: The ChIP results showed that hypoxia-induced HepG2 and Hep3B cell proliferation is mediated by JMJD1A upregulation and subsequent decrease in methylation in the ADM promoter region, suggesting that JMJD 1A might function as a proliferation regulator in some cancer cell types.
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Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice.
Tae Gen Son,Eun Ji Gong,Min Ji Bae,Sung Dae Kim,Kyu Heo,Changjong Moon,Kwangmo Yang,Joong Sun Kim +7 more
TL;DR: Genistein had a protective effect on intestinal damage induced by irradiation and delayed tumor growth, suggesting that genistein is a useful candidate for preventing radiotherapy-induced intestinal damage in cancer patients.
Low-dose radiation activates Nrf1/2 through reactive species and the Ca2+/ERK1/2 signaling pathway in human skin fibroblast cells
TL;DR: LDR induces Nrf1 and Nrf2 activation and expression of Nrf-regulated antioxidant defense genes through RS and Ca2+/ERK1/2 pathways, suggesting new insights into the molecular mechanism underlying the beneficial role of LDR in HS27 cells.
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Novel anti-cancer role of naphthazarin in human gastric cancer cells
Jin-Ah Kim,Eun Kyeong Lee,Seongjoon Park,Nam Deuk Kim,Dong Hoon Hyun,Chang Geun Lee,Jae Ho Lee,Kwangmo Yang,Kyu Heo,Tae Gen Son +9 more
TL;DR: Investigation of the anti-cancer effect of naphthazarin (Naph), one of the naphthaquinones, in human gastric cancer AGS cells showed that Naph not only inhibited cell growth, but also induced apoptosis of AGs cells, suggesting thatNaph may be a potential candidate for cancer therapy against gastric cancers.
Low-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes.
Eon-Seok Lee,Yeo Jin Won,Byoung Chul Kim,Daeui Park,Jin-Han Bae,Seongjoon Park,Sung Jin Noh,Yeong-Rok Kang,Si Ho Choi,Je-Hyun Yoon,Kyu Heo,Kwangmo Yang,Tae Gen Son +12 more
TL;DR: Evidence is provided that miRNA responses to LDIR include the modulation of cellular stress responses and repair mechanisms and the down-regulation of miRNA-193b-3p was down-regulated in the mouse spleen and liver and in various hepatocytes in response toLDIR.