Tadashi Inagami
Vanderbilt University
427 Papers
7.1K Citations
Tadashi Inagami is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Angiotensin II & Renin–angiotensin system. The author has an hindex of 91, co-authored 426 publications. Previous affiliations of Tadashi Inagami include Yale University & Max Delbrück Center for Molecular Medicine.
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Papers
Platelet-derived growth factor AA homodimer stimulates protein synthesis rather than DNA synthesis in vascular smooth muscle cells from spontaneously hypertensive rats but not from normotensive rats.
TL;DR: Results indicate that vascular smooth muscle cell of SHR is uniquely responsive to PDGF-AA, presumably due to abnormality in receptor expression, in its hypertrophic response.
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Changes of AT2 Receptor Levels in the Rat Adrenal Cortex and Medulla Induced by Bilateral Nephrectomy and Its Modulation by Circulating ANG II
Barbara Peters,Susanne Clausmeyer,Philipp Teubner,Nicholas Obermüller,Bettina Kränzlin,Norbert Gretz,Tadashi Inagami,Jörg Peters +7 more
TL;DR: Results demonstrate differential regulation of the AT2 receptor in the adrenal gland and suggest that expression of the At2 receptor is involved in regulating proliferation and differentiation in the ZG and medulla.
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Large Scale Purification of an Endogenous Na+/K+-pump Inhibitor from Bovine Adrenal Glands
Masaaki Tamura,Fumiko Konishi,Masayuki Sakakibara,Tadashi Inagami +3 more
- 01 Jan 1994
TL;DR: The improved procedure for laige scale purification of a Na+/K+-pump inhibitor from bovine adrenal glands is presented, which will enable us to analyze the detailed chemical structure of the inhibitor.
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Angiotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Wayne R. Alexander,Kenneth E. Bernstein,Kevin J. Catt,Marc de Gasparo,Khuraijam Dhanachandra Singh,Satoru Eguchi,Emanuel Escher,Theodore L. Goodfriend,Mastgugu Horiuchi,László Hunyady,Ahsan Husain,Tadashi Inagami,Sadashiva S. Karnik,Jacqueline R. Kemp,Walter G. Thomas,Pieter B.M.W.M. Timmermans,Kalyan C. Tirupula,Hamiyet Unal,Thomas Unger,Patrick Vanderheyden +19 more
- 16 Sep 2019
TL;DR: The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotens in receptors), which have around 30% sequence similarity.
A 45 000 molecular weight human renin precursor is synthesized in a cell-free translation system.
TL;DR: A 15S mRNA has been found to direct synthesis of a 45 000 molecular weight protein immunoprecipitable with anti-human renin, considered to be the ultimate precursor of renin (pre-prorenin).
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