Tabassum Hossain
University of Calcutta
10 Papers
46 Citations
Tabassum Hossain is an academic researcher from University of Calcutta. The author has contributed to research in topics: Docking (molecular) & Pharmacophore. The author has an hindex of 4, co-authored 10 publications.
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Papers
Expedient Synthesis of Biologically Potent Aryloxycoumarins and (Aryloxyimino)ethylcoumarins via Copper(II)-Promoted Chan–Lam Coupling Reaction
TL;DR: In this paper, a convenient protocol for the efficient synthesis of aryloxycoumarins and (aryloxyimino)ethyl coumarin is described, which involves the Cu-promoted C-O and N-O coupling reactions from readily available hydroxycoummarin derivatives in the presence of the catalytic system Cu(OAc)2/Et3N.
14
Exploring structural requirement and binding interactions of β-amyloid cleavage enzyme inhibitors using molecular modeling techniques
TL;DR: The models are adjudged through the docking study elucidating the interactions between the receptor and the ligand, indicating the structural requirements of potent BACE inhibitors.
13
Chemometric design to explore pharmacophore features of BACE inhibitors for controlling Alzheimer's disease
TL;DR: Validated ligand-based pharmacophore mapping was combined with 3D QSAR modeling approaches to identify structural and physico-chemical requirements for a potential BACE inhibitor using a database containing 980 structurally diverse compounds, assembled from different reports.
9
Exploring molecular structural requirement for AChE inhibition through multi-chemometric and dynamics simulation analyses
TL;DR: The aim of the present study is to identify the essential structural and physicochemical profiles of molecules that can provide therapeutic benefits with less toxicity.
7
Molecular modeling on structure-function analysis of human progesterone receptor modulators.
TL;DR: The structure-function characterization is adjudged with the receptor-based docking study, explaining the significance of the mapped molecular attributes for ligand-receptor interaction in the catalytic cleft of PR-A.
4