T. Taguchi
Nagasaki University
16 Papers
242 Citations
T. Taguchi is an academic researcher from Nagasaki University. The author has contributed to research in topics: Transplantation & Heat shock protein 47. The author has an hindex of 11, co-authored 16 publications.
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Papers
•Journal Article
Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung diseases.
TL;DR: It is concluded that overexpression of HSP47 might play an important role in the excessive assembly/synthesis of collagens and could thereby contribute to the fibrosis found in pulmonary fibrotic lung diseases.
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Coexpression of Collagens and Collagen-Binding Heat Shock Protein 47 in Human Diabetic Nephropathy and IgA Nephropathy
TL;DR: It is found that increased levels of HSP47 may play an important role in the excessive assembly of collagens resulting in glomerulosclerosis and interstitial fibrosis found in DN and IgAN patients.
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Age-related nephropathy in the Fischer 344 rat is associated with overexpression of collagens and collagen-binding heat shock protein 47.
TL;DR: It is concluded that overexpression of HSP47 by phenotypically altered renal cells might play an important role in the excessive assembly of collagens and could thereby contribute to the glomerulosclerosis and interstitial fibrosis found in kidneys of aged F 344 rats.
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Cisplatin-induced apoptosis in human proximal tubular epithelial cells is associated with the activation of the Fas/Fas ligand system.
TL;DR: It is indicated that CP treatment induces apoptosis in human PTECs and the activation of the Fas/Fas-L system may play an active role in the induction of the apoptotic cell death process.
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Life-long dietary restriction modulates the expression of collagens and collagen-binding heat shock protein 47 in aged Fischer 344 rat kidney.
M.S. Razzaque,Isao Shimokawa,Arifa Nazneen,Diange Liu,Takashi Naito,Yoshikazu Higami,T. Taguchi +6 more
TL;DR: Examination of the effect of dietary restriction for the expression of collagens and collagen-binding HSP47 in the kidneys of 6- and 24-month-old male Fischer 344 (F 344) rats suggests that increased expression of H SP47 is associated with age-related renal damage and that diet-restricted alteration of its expression isassociated with the modulation of age-associated renal sclerosis/fibrosis.
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