T. Schier
Max Planck Society
13 Papers
200 Citations
T. Schier is an academic researcher from Max Planck Society. The author has contributed to research in topics: Slow-wave sleep & Internal medicine. The author has an hindex of 9, co-authored 13 publications.
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Papers
DHEA administration increases rapid eye movement sleep and EEG power in the sigma frequency range.
TL;DR: DHEA administration has a mixed GABAA-agonistic/antagonistic effect, exerted either directly or through DHEA-induced changes in steroid metabolism, which suggests the potential clinical usefulness of D HEA in age-related dementia.
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Reduced efficacy of growth hormone-releasing hormone in modulating sleep endocrine activity in the elderly.
TL;DR: It is shown that GHRH is capable of promoting sleep in the elderly, but much less than in young subjects, and the hypothalamic-pituitary-adrenocortical system remains unaffected by G HRH inThe elderly.
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VIP decelerates non-REM-REM cycles and modulates hormone secretion during sleep in men
Harald Murck,J. Guldner,M. Colla-Müller,Ralf-Michael Frieboes,T. Schier,Klaus Wiedemann,Florian Holsboer,Axel Steiger +7 more
TL;DR: It appears that VIP may have a phase-advancing effect on sleep cycles and cortisol secretion, possibly through actions that involve the suprachiasmatic nucleus.
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Changes in sleep-endocrine activity after growth hormone-releasing hormone depend on time of administration
TL;DR: It is suggested that the physiological occurring high activity of the hypothalamic‐pituitary‐adrenocortical(HPA) system in the early morning prevents the effects of GHRH on cortisol plasma levels and SWS.
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Galanin has REM-sleep deprivation-like effects on the sleep EEG in healthy young men.
TL;DR: Spectral analysis revealed a significant increase in the EEG power in the delta and theta frequency range for the total night after the lower dose of galanin, but not after the higher dose, and the secretion of growth hormone, cortisol and prolactin remained unchanged during sleep in both cases.
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