Bilateral Orchiectomy With or Without Flutamide for Metastatic Prostate Cancer

Prostate cancer is the second most common malignancy in males and the sixth leading cause of cancer mortality in men with a relatively higher death rate in men of African descent. In the United States and other parts of Europe, more than 80% of diagnosed prostate cancer is localized, and 80-90% of these men receive some form of treatment. The projected data may not be a direct reflection of the disease in the sub-Saharan region as less than 40% presents with localized disease. Results from prostate cancer screening have shown that most African men in the sub-region have little knowledge of the disease. There are recommended international guidelines for the management of localized prostate cancer, however, a guideline in a local context could be ideal. World J Oncol. 2019;10(4-5):162-168 doi: https://doi.org/10.14740/wjon1221

/pdf/a-review-of-localized-prostate-cancer-an-african-perspective-4vm586wah4.pdf

A Review of Localized Prostate Cancer: An African Perspective.

The estimated incidence rate of prostate cancer in Africa was 22.0/100,000 in 2016. The International Agency for Research on Cancer (IARC) has cited prostate cancer as a growing health threat in Africa with approximated 28,006 deaths in 2010 and estimated 57,048 deaths in 2030. The exact incidence of advanced and metastatic prostate cancer is not known in sub-Saharan Africa. Hospital-based reports from the region have shown a rising trend with most patients presenting with advanced or metastatic disease. The management of advanced and metastatic prostate cancer is challenging. The available international guidelines may not be cost-effective for an African population. The most efficient approach in the region has been surgical castration by bilateral orchidectomy or pulpectomy. Medical androgen deprivation therapy is expensive and may not be available. Patients with metastatic castrate-resistant prostate cancer tend to be palliated due to the absence or cost of chemotherapy or second-line androgen deprivation therapy in most of Africa. A cost-effective guideline for developing nations to address the rising burden of advanced prostate cancer is warranted at this moment.

/pdf/management-of-advanced-and-metastatic-prostate-cancer-a-need-33uvrpf4km.pdf

Management of Advanced and Metastatic Prostate Cancer: A Need for a Sub-Saharan Guideline

https://doi.org/10.1016/j.ijscr.2022.106908

Very late diagnosed Retrocaval ureter: A case report of a very rare entity in Cameroon, sub-Sahara Africa

Resume Objectif Decrire les caracteristiques epidemiologiques, anatomiques et cliniques des fistules urogenitales et recto-vaginales ainsi que l’issue de leur prise en charge chirurgicale au Togo. Materiel et methodes Une etude retrospective a collige tous les cas operes sur une periode de cinq ans dans le centre national de prise en charge des fistules obstetricales. Les parametres etudies etaient les donnees sociodemographiques des patientes, les caracteristiques cliniques et l’issue de la reparation chirurgicale. Resultats Le nombre de patientes traitees etait de 197, pour un nombre total de 217 interventions chirurgicales. L’âge moyen des patientes etait de 40,7 ans avec des extremes de 18 et 70 ans. Les causes obstetricales predominaient (95 %) et 3,5 % etaient causees par une chirurgie. Sur le plan anatomo-clinique, la fistule vesico-vaginale (FVV) etait la forme la plus frequente representant 87,3 % tandis que la fistule vesico-uterine n’occupait que 4,1 %. La multiparite etait un facteur de risque de survenue de fistule obstetricale et une cesarienne a ete necessaire dans 70 % marquee par une forte mortalite du fœtus (88,2 %). La prise en charge chirurgicale a ete tardive dans la majorite des cas, avec un delai d’environ 10 ans entre la survenue de la fistule et sa reparation. Le taux de guerison etait de 78,1 %. Conclusion Les fistules urogenitales sont principalement d’origine obstetricale au Togo avec comme facteur de risque la multiparite. La prise en charge est tardive mais permet un bon taux de guerison. Leur prevention passe par la lutte contre la dystocie. Niveau de preuve IV.

Profil épidémiologique, anatomoclinique et thérapeutique des fistules urogénitales et rectovaginales au Togo

https://www.ajol.info/index.php/aju/article/download/136856/126351

Profil épidémiologique, diagnostique, thérapeutique et évolutif du cancer de la prostate au Togo

https://www.ajol.info/index.php/aju/article/download/113420/103141

Complications urologiques de la chirurgie pelvienne au CHU Aristide Le Dantec de Dakar

Notre experience de la prise en charge de la fracture de verge au CHU de Lomé

https://www.ajol.info/index.php/aju/article/download/182269/171647

Morbidité et mortalité après adénomectomies prostatiques par voie transvésicale au CHU Kara (Togo)

https://www.ajol.info/index.php/aju/article/view/150585/140163

Prise en charge de l’uretère rétrocave au Togo: A propos de 3 observations

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