Swaroop S. Singh

TL;DR: Primary xenografts of human benign and CaP tissue transplanted to immunocompromized SCID mice were used to characterize the response of the prostate vasculature to androgen deprivation, and VEGF-A expression by prostate endothelial cells appears to represent a key facilitator of the vascular rebound in human prostate tissue induced by removal of circulating testicular androgens.

TL;DR: Thioredoxin reductase 1 should be targeted in an attempt to delay or prevent CaP recurrence after castration, according to the objective of this study.

TL;DR: The differences measured in the intensity of AR expression in prostate cancer were consistent with previous studies, and classification coefficients are required due to non-standardized immunostaining and image collection methods across medical institutions and research laboratories.

TL;DR: In this article, an optimal sampling strategy for tissue microarrays using automated digital analysis for androgen receptor (heterogeneous expression) and the cellular proliferation marker Ki-67 (homogeneous expression and evaluated by others using nonautomated methods).