Svenja Brode
Free University of Berlin
5 Papers
21 Citations
Svenja Brode is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Aptamer & Locked nucleic acid. The author has an hindex of 3, co-authored 5 publications.
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Papers
Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer.
Charlotte Förster,Arnd B. E. Brauer,Svenja Brode,Kathrin Schmidt,Markus Perbandt,Arne Meyer,Wojciech Rypniewski,Christian Betzel,Jens Kurreck,Jens P. Fürste,Volker A. Erdmann +10 more
TL;DR: Here, the crystallographic and X-ray diffraction data of the isolated aptamer stem encompassed in a six-base-pair duplex both with and without the LNA modification are presented.
tRNASer acceptor stem: conformation and hydration of a microhelix in a crystal structure at 1.8 Å resolution
Charlotte Förster,Arnd B. E. Brauer,Svenja Brode,Jens P. Fürste,Christian Betzel,Volker A. Erdmann +5 more
TL;DR: The crystal structure of a serine-specific tRNA acceptor-stem microhelix, the binding site for the seryl-tRNA synthetase, was solved by X-ray analysis and the role of the specific hydration pattern and of the irregular conformation of the tRNA(Ser) acceptor -stem helix is discussed and summarized.
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Crystallization and preliminary X-ray diffraction analysis of an Escherichia coli tRNAGly acceptor-stem microhelix
Charlotte Förster,Markus Perbandt,Arnd B. E. Brauer,Svenja Brode,Jens P. Fürste,Christian Betzel,Volker A. Erdmann +6 more
TL;DR: To obtain further insight concerning structural investigation of the identity elements of the tRNA identity elements, the Escherichia coli seven-base-pair tRNA(Gly) acceptor-stem helix was crystallized.
Crystallization and preliminary X-ray diffraction analysis of a tRNASer acceptor-stem microhelix.
Charlotte Förster,Norbert Krauss,Arnd B. E. Brauer,Karol Szkaradkiewicz,Svenja Brode,Klaus Hennig,Jens P. Fürste,Markus Perbandt,Christian Betzel,Volker A. Erdmann +9 more
TL;DR: The synthesis, crystallization and preliminary X-ray diffraction results for a seven-base-pair tRNA(Ser) acceptor-stem helix are presented here.
Cocrystallizing natural RNA with its unnatural mirror image: biochemical and preliminary X-ray diffraction analysis of a 5S rRNA A-helix racemate.
Charlotte Förster,Arnd B. E. Brauer,Daniel Lehmann,Tordis Borowski,Svenja Brode,Jens P. Fürste,Markus Perbandt,Christian Betzel,Volker A. Erdmann +8 more
TL;DR: For a structural comparison, both L- and D-RNA oligonucleotides of a shortened Thermus flavus 5S rRNA A-helix were chemically synthesized and stochiometrically cocrystallized as a racemate, which enabled analysis of the D- and L-RNA enantiomers in the same crystals.