Sven Laarmann
University of Münster
4 Papers
Sven Laarmann is an academic researcher from University of Münster. The author has contributed to research in topics: Bacterial adhesin & Secretion. The author has an hindex of 4, co-authored 4 publications.
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Papers
Characterization of translocation pores inserted into plasma membranes by type III‐secreted Esp proteins of enteropathogenic Escherichia coli
TL;DR: These results, together with the homologies of EspB and EspD to proposed functional domains of other pore‐forming proteins (Yop/Ipa), strongly support the idea that both proteins are directly involved in pore formation, which might represent the type III secretion system translocon.
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The Escherichia coli AIDA autotransporter adhesin recognizes an integral membrane glycoprotein as receptor.
TL;DR: It is demonstrated that the purified adhesin binds specifically to a high-affinity class of receptors on HeLa cells, indicating a broad tissue distribution of the receptor moiety.
58
Diffusely adhering Escherichia coli strains induce attaching and effacing phenotypes and secrete homologs of Esp proteins
TL;DR: Some DAEC strains are likely to contain a homolog(s) of the LEE locus which may contribute to the pathogenic potential of DAEC, and these results indicate that secretion of the Esp proteins alone is not sufficient for efficient signal transduction.
Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2
Nicole Zobiack,Ursula Rescher,Sven Laarmann,Silke Michgehl,M. Alexander Schmidt,Volker Gerke +5 more
TL;DR: It is shown that adherent EPEC microcolonies, which are known to induce the formation of actin-rich pedestals beneath them, specifically recruit annexin 2 to the sites of their attachment, which indicates that membrane components present in rafts or raft-like microdomains are clustered upon EPEC adherence and that Annexin 2 is recruited to the cytoplasmic membrane surface of such clusters.