Susan Maddocks
Westmead Hospital
35 Papers
111 Citations
Susan Maddocks is an academic researcher from Westmead Hospital. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 14, co-authored 25 publications. Previous affiliations of Susan Maddocks include University of Sydney & Ministry of Health (New South Wales).
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Papers
Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling.
Rebecca J. Rockett,Rebecca J. Rockett,Alicia Arnott,Alicia Arnott,Alicia Arnott,Connie Lam,Connie Lam,Rosemarie Sadsad,Rosemarie Sadsad,Verlaine J. Timms,Verlaine J. Timms,Karen-Ann Gray,Karen-Ann Gray,John-Sebastian Eden,Sheryl L. Chang,Mailie Gall,Jenny Draper,Eby Sim,Eby Sim,Nathan L. Bachmann,Nathan L. Bachmann,Ian Carter,Kerri Basile,Roy Byun,Matthew V. N. O'Sullivan,Matthew V. N. O'Sullivan,Matthew V. N. O'Sullivan,Sharon C.-A. Chen,Sharon C.-A. Chen,Sharon C.-A. Chen,Susan Maddocks,Tania C. Sorrell,Tania C. Sorrell,Dominic E. Dwyer,Dominic E. Dwyer,Dominic E. Dwyer,Edward C. Holmes,Jen Kok,Jen Kok,Jen Kok,Mikhail Prokopenko,Vitali Sintchenko +41 more
TL;DR: The prospective sequencing of SARS-CoV-2 clarified the probable source of infection in cases where epidemiological links could not be determined, significantly decreased the proportion of COVID-19 cases with contentious links, documented genomically similar cases associated with concurrent transmission in several institutions and identified previously unsuspected links.
Safety of bacteriophage therapy in severe Staphylococcus aureus infection
Aleksandra Petrovic Fabijan,Ruby C.Y. Lin,Josephine Ho,Susan Maddocks,Susan Maddocks,Nouri L. Ben Zakour,Jonathan R. Iredell,Jonathan R. Iredell,Westmead Bacteriophage Therapy Team +8 more
TL;DR: The data indicate that AB-SA01 administered in this way is safe in severe S. aureus infections, including infective endocarditis and septic shock, and the measurements of bacterial and phage kinetics in blood samples suggest that 12 h dosing of 109 plaque-forming units may be a rational basis for further studies.
354
HIV-1 infection of human macrophages directly induces viperin which inhibits viral production
Najla Nasr,Susan Maddocks,Stuart Turville,Andrew N. Harman,Natalie Woolger,Karla J. Helbig,John Wilkinson,Christopher R. Bye,Thomas K. Wright,Dharshini Rambukwelle,Heather Donaghy,Michael R. Beard,Anthony L. Cunningham +12 more
TL;DR: Mutagenesis analysis in transfected cell lines showed that the internal S-adenosyl methionine domains of viperin were essential for its antiviral activity, which may contribute to persistent noncytopathic HIV-1 infection of macrophages and possibly to biologic differences with HIV- 1-infected T cells.
229
Bacteriophage Therapy of Ventilator-associated Pneumonia and Empyema Caused by Pseudomonas aeruginosa
Susan Maddocks,Aleksandra Petrovic Fabijan,Josephine Ho,Ruby C.Y. Lin,Nouri L. Ben Zakour,Chris Dugan,Ivana Kliman,Steven Branston,Sandra Morales,Jonathan R. Iredell +9 more
TL;DR: Bacteriophage therapy was first used as antibacterial therapy in the early 1900s, and interest in its therapeutic potential has been renewed with the development of increasing antimicrobial resistance globally.
104
Cell-based culture of SARS-CoV-2 informs infectivity and safe de-isolation assessments during COVID-19
Kerri Basile,K McPhie,Ian Carter,S Alderson,H Rahman,L Donovan,S Kumar,T Tran,D Ko,T Sivaruban,C Ngo,C Toi,Matthew V. N. O'Sullivan,Matthew V. N. O'Sullivan,Matthew V. N. O'Sullivan,Vitali Sintchenko,Vitali Sintchenko,Vitali Sintchenko,S.C-A. Chen,S.C-A. Chen,S.C-A. Chen,Susan Maddocks,Dominic E. Dwyer,Dominic E. Dwyer,Dominic E. Dwyer,Jen Kok,Jen Kok +26 more
TL;DR: SARS-CoV-2 culture may be used as a surrogate marker for infectivity and inform de-isolation protocols and in samples with lower Ctsample values.
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