Susan E. Bergeson
Texas Tech University Health Sciences Center
19 Papers
17 Citations
Susan E. Bergeson is an academic researcher from Texas Tech University Health Sciences Center. The author has contributed to research in topics: Alcohol use disorder & Chronic pain. The author has an hindex of 10, co-authored 19 publications.
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Papers
Minocycline reduces ethanol drinking.
TL;DR: The results suggest that drugs that alter neuroimmune pathways may represent a new approach to developing additional therapies to treat alcoholism and suggest that neuroimmune activity of brain glia may have a role in drinking.
Differential Sensitivity of Prefrontal Cortex and Hippocampus to Alcohol-Induced Toxicity
Anna-Kate Fowler,Jeremy M. Thompson,Lixia Chen,Marisela Dagda,Janet Dertien,Katina Sylvestre S. Dossou,Ruin Moaddel,Susan E. Bergeson,Inna I. Kruman +8 more
TL;DR: It is demonstrated that the PFC is more vulnerable to chronic alcohol-induced oxidative stress and neuronal cell death than the hippocampus, evidenced by elevated oxidative stress-induced DNA damage and enhanced expression of apoptotic markers in PFC neurons.
DNA damage and neurotoxicity of chronic alcohol abuse.
TL;DR: The role of DNA damage and DNA repair dysfunction in chronic alcohol-induced neurodegeneration is outlined and both DNA repair and DNA methylation are critical for maintaining genomic stability.
Binge Ethanol Consumption Increases Inflammatory Pain Responses and Mechanical and Cold Sensitivity: Tigecycline Treatment Efficacy Shows Sex Differences
Susan E. Bergeson,Henry L. Blanton,Joseph M. Martinez,David C. Curtis,Caitlyn Sherfey,Brandon Seegmiller,Patrick C. Marquardt,Jessica A. Groot,Clayton L. Allison,Christian Bezboruah,Josée Guindon +10 more
TL;DR: It is demonstrated that binge drinking increases pain, touch, and thermal sensations in both sexes and sex‐specific effects of tigecycline on inflammatory pain, as well as mechanical and cold sensitivities are identified.
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Tigecycline Reduces Ethanol Intake in Dependent and Nondependent Male and Female C57BL/6J Mice
TL;DR: The data suggest that tigecycline may be a promising drug with novel pharmacotherapeutic characteristics for the treatment of mild-to-severe AUD in both sexes.