Surinder Singh
King's College London
20 Papers
650 Citations
Surinder Singh is an academic researcher from King's College London. The author has contributed to research in topics: Peroxynitrite & Transferrin. The author has an hindex of 13, co-authored 20 publications.
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Papers
Inhibition of Peroxynitrite Dependent Tyrosine Nitration by Hydroxycinnamates: Nitration or Electron Donation?
TL;DR: In this paper, the ability of hydroxycinnamate antioxidants to decrease peroxynitrite-mediated nitration of tyrosine was investigated, and the results showed that all compounds were able to inhibit nitration.
223
A direct method for quantification of non-transferrin-bound iron
TL;DR: This assay relies on the use of a large excess of a low affinity ligand which removes and complexes all low molecular weight iron and iron nonspecifically bound to serum proteins.
152
Interaction of peroxynitrite with carotenoids and tocopherols within low density lipoprotein
TL;DR: It was observed that the carotenoids were consumed by a significantly greater proportion than that of the tocopherols with lycopene being more reactive than β‐carotene when exposed to peroxynitrite (50 μM) for 1 min.
70
Separation and identification of desferrioxamine and its iron chelating metabolites by high-performance liquid chromatography and fast atom bombardment mass spectrometry: Choice of complexing agent and application to biological fluids
TL;DR: The identity of the iron chelating metabolites of DFO present in the urine of patients with beta-thalassemia major has been established using FAB mass spectrometry and a metabolite which corresponds to N-hydroxylation of the terminal amino group has been identified.
48
Patent
3-hydroxy-pyridin-4-ones useful for treating parasitic infections
Robert C. Hider,Tim E. A. Peto,Surinder Singh,Susan Whitehead +3 more
- 24 Jul 1992
TL;DR: In this article, the authors proposed an approach for the treatment of conditions caused by iron dependent parasites, particularly malaria, with the proviso that the total number of carbon atoms in R 1 to R 4 is no more than six, the compound optionally being in the form of a physiologically acceptable salt and/or pro-drug thereof.
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