Sunil Krishnan
University of Texas Health Science Center at Houston
19 Papers
73 Citations
Sunil Krishnan is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Radiation therapy & Pancreatic cancer. The author has an hindex of 7, co-authored 19 publications. Previous affiliations of Sunil Krishnan include University of Texas at Austin.
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Papers
Focal Radiation Therapy Dose Escalation Improves Overall Survival in Locally Advanced Pancreatic Cancer Patients Receiving Induction Chemotherapy and Consolidative Chemoradiation
Sunil Krishnan,Awalpreet S. Chadha,Yelin Suh,Hsiang Chun Chen,Arvind Rao,Prajnan Das,B.D. Minsky,Usama Mahmood,Marc E. Delclos,Gabriel O. Sawakuchi,Sam Beddar,Matthew H.G. Katz,Jason B. Fleming,Milind Javle,Gauri R. Varadhachary,Robert A. Wolff,Christopher H. Crane +16 more
TL;DR: Radiation dose escalation during consolidative chemoradiation therapy after induction chemotherapy for LAPC patients improves OS and local-regional RFS and higher dose was the only predictor of improved OS on multivariate analysis.
Therapeutic Significance of Elevated TissueTransglutaminase Expression in Pancreatic Cancer
Amit Verma,Sushovan Guha,Parmeswaran Diagaradjane,Ajaikumar B. Kunnumakkara,Angela Sanguino,Gabriel Lopez-Berestein,Anil K. Sood,Bharat B. Aggarwal,Sunil Krishnan,Juri G. Gelovani,Kapil Mehta +10 more
- 01 Jan 2008
TL;DR: It is shown that down-regulation of endogenous TG2 by siRNA could effectively block the growth of PDAC and significantly enhanced the therapeutic efficacy of gemcitabine againstPDAC and inhibited metastatic spread of the disease.
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Quantified pathologic response assessed as residual tumor burden is a predictor of recurrence-free survival in patients with rectal cancer who undergo resection after neoadjuvant chemoradiotherapy.
Atin Agarwal,George J. Chang,Chung Yuan Hu,Melissa W. Taggart,Asif Rashid,In J. Park,Y. Nancy You,Prajnan Das,Sunil Krishnan,Christopher H. Crane,Miguel A. Rodriguez-Bigas,John M. Skibber,Lee M. Ellis,Cathy Eng,Scott Kopetz,Dipen M. Maru +15 more
TL;DR: The current study was conducted to determine whether quantified pathologic response assessed as a percentage of residual tumor cells is predictive of recurrence‐free survival (RFS) in patients with rectal cancer.
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Recent Advances and Prospects for Multimodality Therapy in Pancreatic Cancer
Awalpreet S. Chadha,Allison Khoo,Maureen L. Aliru,Harpreet Kaur Arora,Jillian R. Gunther,Sunil Krishnan +5 more
TL;DR: The outcomes for treatment of pancreatic cancer have not improved dramatically in many decades, but the recent promising results with combination chemotherapy regimens for metastatic disease increase optimism for future treatments.
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Short course radiation as a component of definitive multidisciplinary treatment for select patients with metastatic rectal adenocarcinoma.
E. Holliday,Andrew Hunt,Y. Nancy You,George J. Chang,John M. Skibber,Miguel A. Rodriguez-Bigas,Brian K. Bednarski,Cathy Eng,Eugene J. Koay,B.D. Minsky,Cullen M. Taniguchi,Sunil Krishnan,Joseph M. Herman,Prajnan Das +13 more
TL;DR: Findings suggest that SCRT can be successfully integrated into a definitive, multidisciplinary approach to metastatic rectal adenocarcinoma, and benefits to this approach include decreased time off systemic therapy as compared to standard course RT.