Sunil Dhar
New Jersey Institute of Technology
16 Papers
20 Citations
Sunil Dhar is an academic researcher from New Jersey Institute of Technology. The author has contributed to research in topics: Pressure overload & Multinomial test. The author has an hindex of 7, co-authored 16 publications.
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Papers
Concurrent vision dysfunctions in convergence insufficiency with traumatic brain injury.
TL;DR: Convergence insufficiency without simultaneous visual or vestibular dysfunctions was observed in about 9% of the visually symptomatic TBI civilian population studied.
Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload
Nadia Hedhli,Paulo Lizano,Chull Hong,Luke F. Fritzky,Sunil Dhar,Huasheng Liu,Yimin Tian,Shumin Gao,Kiran Madura,Stephen F. Vatner,Christophe Depre +10 more
TL;DR: It is proposed that proteasome inhibition after the onset of pressure overload rescues ventricular remodeling by stabilizing cardiac function, suppressing further progression of hypertrophy, repressing collagen accumulation, and reducing myocyte apoptosis.
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Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload
Aziz Guellich,Shumin Gao,Chull Hong,Lin Yan,Thomas E. Wagner,Sunil Dhar,Bijan Ghaleh,Luc Hittinger,Kosaku Iwatsubo,Yoshihiro Ishikawa,Stephen F. Vatner,Dorothy E. Vatner +11 more
TL;DR: In contrast to other interventions previously reported to be salutary with cardiac AC6 overpression, the response to chronic pressure overload was not; actually, AC6 TG mice fared worse than WT mice, which may be due to the increased LV systolic wall stress in AC6TG mice with chronic pressure overloaded.
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Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting
TL;DR: This preliminary report is to examine additional clinical hemodynamic calculations of compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi) using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters.
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Inhibition of Smooth Muscle Myosin as a Novel Therapeutic Target for Hypertension
Xin Zhao,David Ho,Patricio Abarzúa,Sunil Dhar,Xi Wang,Zhiheng Jia,Malar Pannirselvam,David J. Morgans,Fady I. Malik,Stephen F. Vatner +9 more
TL;DR: The smooth muscle myosin inhibitor's preferential effect on renal blood flow makes this drug mechanism particularly appealing, because many patients with hypertension have renal insufficiency, and patients with heart failure could benefit from afterload reduction coupled with enhanced renalBlood flow.
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