Sunghoon Lee
Genome Research Foundation
22 Papers
48 Citations
Sunghoon Lee is an academic researcher from Genome Research Foundation. The author has contributed to research in topics: Gene & Fusion gene. The author has an hindex of 10, co-authored 22 publications. Previous affiliations of Sunghoon Lee include Korea Research Institute of Bioscience and Biotechnology.
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Papers
The tiger genome and comparative analysis with lion and snow leopard genomes
Yun Sung Cho,Li Hu,Haolong Hou,Hang Lee,Jiaohui Xu,Soowhan Kwon,Sukhun Oh,Hak-Min Kim,Sungwoong Jho,Sangsoo Kim,Young Ah Shin,Byung Chul Kim,Hyunmin Kim,Chang Uk Kim,Shu-Jin Luo,Warren E. Johnson,Klaus-Peter Koepfli,Anne Schmidt-Küntzel,Jason A. Turner,Laurie Marker,Cindy Kim Harper,Susan M. Miller,Susan M. Miller,Wilhelm Jacobs,Laura D. Bertola,Tae Hyung Kim,Sunghoon Lee,Qian Zhou,Hyun Ju Jung,Xiao Xu,Priyvrat Gadhvi,Pengwei Xu,Yingqi Xiong,Yadan Luo,Shengkai Pan,Caiyun Gou,Xiuhui Chu,Jilin Zhang,Sanyang Liu,Jing He,Ying Chen,Linfeng Yang,Yulan Yang,Jiaju He,Sha Liu,Junyi Wang,Chulhong Kim,Hwanjong Kwak,Jong-Soo Kim,Seungwoo Hwang,Junsu Ko,Chang Bae Kim,Sangtae Kim,Damdin Bayarlkhagva,Woon Kee Paek,Seong-Jin Kim,Stephen J. O'Brien,Stephen J. O'Brien,Jun Wang,Jun Wang,Jong Bhak +60 more
TL;DR: Comparison genetic analyses of the genomes of a white Bengal tiger, African lion, white African lion and snow leopard find genetic signatures that may reflect molecular adaptations consistent with the big cats’ hypercarnivorous diet and muscle strength.
Genomic profile analysis of diffuse-type gastric cancers
Yeon-Su Lee,Yun Sung Cho,Geon Kook Lee,Sunghoon Lee,Young-Woo Kim,Sungwoong Jho,Hak-Min Kim,Seung-Hyun Hong,Jung Ah Hwang,Sook Young Kim,Dongwan Hong,Il Ju Choi,Byung Chul Kim,Byoung Chul Kim,Chulhong Kim,Hansol Choi,Young Ju Kim,Kyung Wook Kim,Gu Kong,Hyung Lae Kim,Jong Bhak,Seung Hoon Lee,Jin Soo Lee +22 more
TL;DR: The genomic profile of diffuse-type gastric cancers is reported including new somatic variations, a novel fusion gene, and amplification and deletion of certain chromosomal regions that contain oncogenes and tumor suppressors.
SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: whole-genome analysis in patients with hepatocellular carcinoma
Yeon-Su Lee,Bohyun Kim,Byung Chul Kim,Aesun Shin,Jin Sook Kim,Seung-Hyun Hong,Jung Ah Hwang,Jung Ahn Lee,Seungyoon Nam,Sunghoon Lee,Jong Bhak,Jong Bhak,Joong-Won Park +12 more
TL;DR: The finding using extreme responder seems to generate robust biomarker to predict the response of sorafenib treatment for HCC.
PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling
Yun Sm,Yoon K,Sunghoon Lee,Kim E,Kong Sh,Choe J,Jin Muk Kang,Tae-Su Han,Kim P,Choi Y,Jho S,Yoo H,Bhak J,Han-Kwang Yang,Seong-Jin Kim +14 more
TL;DR: Findings show that PPP1R1B-STARD3 fusion transcript has a key role in subsets of gastric cancers through the activation of PI3K/AKT signaling.
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Barcode System for Genetic Identification of Soybean [Glycine max (L.) Merrill] Cultivars Using InDel Markers Specific to Dense Variation Blocks.
Hwang-Bae Sohn,Su-Jeong Kim,Tae-Young Hwang,Hyang-Mi Park,Yu-Young Lee,Kesavan Markkandan,Dongwoo Lee,Sunghoon Lee,Su-Young Hong,Yun-Ho Song,Bon-Cheol Koo,Yul-Ho Kim +11 more
TL;DR: The results indicate that the soybean barcode system enables not only the minimal use of molecular markers but also comparing the data from different sources due to no need of exploiting allele binning in new varieties.